Candida Antigen Immunotherapy Versus Steroid in the Treatment of Alopecia Areata

    January 2021 in “ Dermatologic Therapy ”
    Samia Taher Ali, Al‐shimaa M. Ibrahim, Noura El Sayed
    TLDR Candida antigen is an effective and promising treatment for alopecia areata.
    The study compared the efficacy of Candida antigen immunotherapy to intralesional steroids in treating alopecia areata (AA) in 48 adult patients. Patients were divided into two groups: one received monthly injections of Candida albicans antigen, and the other received triamcinolone acetonide. After 5 months, both treatments significantly reduced the severity of AA with no significant difference between the groups. In the Candida group, 8 patients experienced complete hair regrowth, and 9 had partial regrowth. Side effects were mild and less frequent in the Candida group. The study concluded that intralesional Candida antigen is a promising and effective treatment for AA.
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