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Genetic variations greatly affect individual metabolism and can impact health and disease risk.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Idiopathic hirsutism causes excessive hair growth in women, can be treated with medication and hair removal, but cannot be fully reversed.

Child with rickets improved with a specific vitamin D therapy, but alopecia did not change.

Testosterone therapy for postmenopausal women appears safe and may protect against heart disease, but requires constant monitoring and more research for long-term effects.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

Levothyroxine is less effective in men with early-onset male-pattern baldness.

A man's low testosterone and related symptoms improved after he stopped taking hair loss drugs.

The document suggests that there might be an autoimmune link between polycystic ovary syndrome and Graves' disease.

Women with PCOS have more Bifidobacterium in their gut compared to those without PCOS.

Men, particularly those with hair loss, are more likely to get the virus, and those with prostate cancer may have milder symptoms. Testosterone's role in the disease is unclear, and the virus doesn't seem to harm male fertility. Women with PCOS might be at higher risk. More research is needed.

Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

Taking 1mg of finasteride daily can mildly improve metabolic health and glucose regulation in men with male pattern baldness.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

A toddler with a rare adrenal gland tumor causing male-like physical changes was successfully treated with surgery.

The birth control combination of ethinylestradiol and drospirenone helps treat symptoms of polycystic ovary syndrome.

Polycystic ovary syndrome and iron overload share similar symptoms and can be potentially treated with blood removal, diet changes, and probiotics.

Multi-omics techniques help understand the molecular causes of androgenetic alopecia.

Patterned hair loss in women is linked to hormonal imbalances and biochemical changes, and should be evaluated for underlying health issues.

Testosterone is linked to cardiovascular risk factors and stroke, but its exact role is unclear.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

The conclusion is that thorough investigation of hypertension and hormonal dysfunctions is important, and there may be a link between these conditions and cancer.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

The severity of symptoms in nonclassical congenital adrenal hyperplasia is not determined by CYP21A2 gene variations.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.