Search

everythinglearnresearchcommunity

for

Search:↓

New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Certain drugs that block specific enzymes can help treat prostate diseases.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Finasteride changes antioxidant enzyme expression, possibly affecting sperm protection in rats.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.

Compound 4 is a promising treatment for hair loss with low toxicity.

The enzyme sEH is important for hair growth and its inhibition could help treat hair loss.

The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Low-potency steroids can cause serious side effects in people with skin conditions like Netherton syndrome.

A woman's liver was damaged by taking the herbal supplement Shou-Wu-Pian, but it got better after she stopped using it.

Finasteride effectively blocks enzyme causing male pattern baldness.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.