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Hair loss in men may be caused by inflammation triggered by hormones, and treatments reducing inflammation could potentially promote hair growth.

Four-amino acid part makes enzyme sensitive to finasteride.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Dihydrotestosterone (DHT) and its active metabolites play a key role in various diseases, and the development of 5α-reductase inhibitors can help treat these conditions.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

Long-term finasteride use doesn't change bone density or metabolism.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.

Finasteride helps treat hair loss by blocking enzyme activity.

New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.

Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.

AGA treatments like minoxidil and LLLLT are safe and effective for gender minority patients.

Diagnosing and treating PCOS in teenagers is difficult, and the focus is on lifestyle changes and medication to improve health and prevent future issues.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

Men and women have different levels and production of brain steroids, which may affect their risk for certain brain disorders.