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Flutamide, dutasteride, and finasteride dissolve differently in supercritical carbon dioxide, with dutasteride dissolving the least.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

New microneedles deliver drugs through the skin accurately and effectively.

Retinoids may help treat lupus nephritis and reduce steroid use.

The congress concluded that misuse of antifungal drugs in South Asia has led to widespread treatment failure, and new approaches and regional cooperation are needed.

The chapter explains the causes of excessive hair growth and masculinization in women and how to measure hormone levels related to these conditions.

Clinicians should use social and prescription data to track trends in performance-enhancing drug use.

Younger patients and those with more hair loss are less likely to benefit from oral steroid treatment for hair loss, and low vitamin D may predict relapse.

Tyrosine kinase inhibitors show promise in treating some skin diseases but their definitive role in dermatology is still unclear.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

A new green method accurately measures finasteride and tadalafil in drugs and plasma.

Many women who have used performance-enhancing drugs in Finland show high rates of mental health and substance use issues, and most have normal red blood cell counts.

Nanostructured delivery systems could potentially improve hair loss treatment by targeting drugs to hair follicles, reducing side effects and dosage, but the best size, charge, and materials for these systems need further investigation.

Anifrolumab treatment improves quality of life and reduces disease activity and steroid use in SLE patients.

A man's low testosterone and related symptoms improved after he stopped taking hair loss drugs.

The document concludes that new treatments for skin conditions are complex but effective, including spironolactone for female hair loss and propranolol for infantile hemangiomas.

Various skin conditions like cutaneous lupus erythematosus, psoriasis, and basal cell carcinoma can be effectively treated with antihypertensive agents, NB-UVB phototherapy, and imiquimod cream respectively. Vaccines are effective against genital herpes and HPV-16 infection. Early intervention is crucial for conditions like diabetic foot ulcers and neonatal herpes. Certain dyes can cause hand dermatitis, and there's a link between smoking/drinking and psoriasis in men. No direct link was found between low iron levels and chronic hair loss in women.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Flutamide reduces hair growth better but has more side effects.

Blocking CRF-R1 can reduce alcohol intake in stressed mice.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

Herbal alternatives like saw palmetto and green tea may offer safe, effective treatment for hormonal hair loss.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Dutasteride and finasteride affect different cell types differently.

New nanocarriers improve skin drug delivery with low toxicity at certain concentrations.