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5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

Dutasteride injections can help hair growth in androgenic alopecia but need more research for long-term use.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Hair loss can be treated with common methods like minoxidil and finasteride, but new potential treatments include growth factors, cytokines, and platelet-rich plasma injections.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Both drugs lower DHT levels, with GI198745 being more effective.

Finasteride microspheres help reduce hair loss for up to eight weeks with fewer side effects.

The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.

Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.

DHT affects testicular development and regulates spermatogenesis in some fish.

Finasteride potentially treats hair loss by reducing DHT production.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose can help treat hair loss by reducing certain hormones and promoting hair growth.

Finasteride helps protect brain in old male rats.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Finasteride helps treat hair loss by blocking enzyme activity.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.

Treatments for hair loss include hormone modifiers, minoxidil, and hair transplant surgery.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.