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Finasteride in male rats causes liver and metabolic issues in their offspring.

The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.

Pumpkin seed oil may help hair grow and could be an alternative treatment for male hair loss.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

Dihydrotestosterone (DHT) and its active metabolites play a key role in various diseases, and the development of 5α-reductase inhibitors can help treat these conditions.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Finasteride effectively treats male pattern hair loss with a 1 mg daily dose.

Male children's genital development issues can be caused by genetic mutations or environmental factors affecting hormone action.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Sleep, testosterone levels, and a specific enzyme activity affect skin oil production in women.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

Androgens may influence bladder cancer progression by affecting cellular behavior.

A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

A new plant extract from Avicennia marina could potentially be used to treat common hair loss.

Dicentrine reduced heart disease risk factors in rats, T-588 protected mice brains without side effects, Provir blocked herpes virus and lessened mouse symptoms, and LY191704 could treat hair loss and prostate issues.