research HtrA1L364P Leads to Cognitive Dysfunction and Vascular Destruction Through TGF-β/Smad Signaling Pathway in CARASIL Model Mice
The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.
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research Prospective Cardiovascular Evaluation with 24-Hour Holter and Ambulatory Blood Pressure Monitoring in Men Using 5-mg Oral Minoxidil for Androgenetic Alopecia
The conclusion is that 24 weeks of low-dose oral minoxidil is safe for men with hair loss, with no significant changes in heart rate or blood pressure.
research A Study of Correlation of Angiographic Evaluation of Coronary Artery Disease with Androgenetic Alopecia – TricoHeart Study
Female pattern baldness may indicate a higher risk of coronary artery disease.
research Hypertension's 3 Dilemmas and 3 Solutions: Pharmacology of the Kidney in Hypertension
Re-evaluating minoxidil, reducing sodium intake, and addressing arteriolar hypertrophy can improve hypertension management.
research Glycosaminoglycans’ Ability to Promote Wound Healing: From Native Living Macromolecules to Artificial Biomaterials
Glycosaminoglycans help heal wounds but aren't yet ready for clinical use.
research Plumbagin, A Natural Compound With Several Biological Effects And Anti-Inflammatory Properties
Plumbagin may help protect cells, reduce inflammation, and has potential for treating various diseases, but more research is needed.
research The Distribution of Preputial Vessels in Different Severity of Rat Congenital Hypospadias Model: Imaging Study Using Micro-Computerized Tomography
The junction of the inner and outer prepuce with good blood flow is ideal for surgical flaps.
research Biomimetic Scaffolds: A Novel Approach to Three-Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering
Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.
research Stabilization of Epithelial Beta-Catenin Compromises Mammary Cell Fate Acquisition and Branching Morphogenesis
Keeping β-catenin levels high in mammary cells disrupts their development and branching.
research Case Report: Heterozygous Mutation in HTRA1 Causing Typical Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy
A heterozygous mutation in HTRA1 can cause severe CARASIL symptoms.
research Advances and Challenges in Plant Sterol Research: Fundamentals, Analysis, Applications and Production
Plant sterols have health benefits like lowering cholesterol, but more research is needed to understand their effects and improve their extraction and sustainability.
research Beard Alopecia: An Updated and Comprehensive Review of Etiologies, Presentation and Treatment
Different causes of beard hair loss have various treatments, including medications, lifestyle changes, and procedures to stimulate hair growth.
research Abstracts From The 55th European Society Of Human Genetics Conference: E-Posters
Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.
research Obesity in Adults: Position Statement of Various Polish Medical Associations
The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.
research Floral Attractants in the Black Orchid Brasiliorchis Schunkeana: Clues for Presumed Sapromyophily and Potential Antimicrobial Activity
The black orchid Brasiliorchis schunkeana produces chemicals that attract certain insects and have potential antimicrobial properties.
research Case Report: Extensive Digital Gangrene as a Primary Manifestation of Late-Onset Systemic Lupus Erythematosus
Digital gangrene can be an initial symptom of late-onset systemic lupus erythematosus.
research Association Between Androgenetic Alopecia and Psychosocial Disease Burden: A Cross-Sectional Survey Among Polish Men
Androgenetic alopecia negatively affects self-esteem and daily stress, especially in young men.
research The Protective Effect of the Crosstalk Between Zinc Hair Concentration and Lymphocyte Count: Preliminary Report
Zinc levels and lymphocyte counts might be important in heart disease development.
research Advancements in Regenerative Medicine for Aesthetic Dermatology: A Comprehensive Review and Future Trends
New regenerative techniques show promise for improving skin, healing wounds, and growing hair.
research The Role and Prospects of Mesenchymal Stem Cells in Skin Repair and Regeneration
Mesenchymal stem cells show promise for effective skin repair and regeneration.
research Animals in Dermatology
Using animal names for skin conditions helps with learning and memory.
research Central Retinal Vein Occlusion with Secondary Cilioretinal Artery Occlusion Following Oral Minoxidil Use: A Case Report and Literature Review
Oral Minoxidil can cause serious eye problems, but stopping it can improve vision.
research Cutaneous Manifestations in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy: A Comprehensive Review
The review shows that skin symptoms like chronic fungal infections, hair loss, and skin depigmentation are key for early detection and management of APECED.
research Relationship Between Copper, Zinc, and Copper-to-Zinc Ratio in Hair and Severity of Coronary Artery Disease According to the SYNTAX Score
Lower hair copper and copper-to-zinc ratio are linked to more severe coronary artery disease.
research Thrombophilia and Polycythemia in a Woman With Budd-Chiari Syndrome
A woman with Budd-Chiari syndrome improved after treatment and needs a liver transplant, highlighting the importance of considering non-criteria antiphospholipid syndrome in similar cases.
research Finasteride and Dutasteride for the Treatment of Male Androgenetic Alopecia: A Review of Efficacy and Reproductive Adverse Effects
Finasteride and Dutasteride can improve hair growth in male baldness but may cause temporary sexual dysfunction and possibly affect fertility.
research Therapeutic Potential of Adult Platelets and Cord Blood Platelets in Future Clinical Directions
Cord blood platelets may have promising future medical uses but need more research.
research Tracing Immune Cells Around Biomaterials With Spatial Anchors During Large-Scale Wound Regeneration
Immune cells are essential for skin regeneration using biomaterial scaffolds.
research Development and Prospective Applications of 3D Membranes as a Sensor for Monitoring and Inducing Tissue Regeneration
3D-printed membranes with smart sensors can greatly improve tissue healing and have many medical applications.
research Liposome-Based Carriers for CRISPR Genome Editing
Liposomes show promise for delivering CRISPR for gene editing but face challenges like delivery efficiency and safety concerns.