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This study observed nestin-GFP expressing stem cells in the hair follicle bulge of living mice using high-resolution in-vivo multiphoton tomography, allowing migration tracking within their natural skin environment.

The researchers reported that conditioned media from deer antler mesenchymal stem cells may enhance hair and skin regeneration by modulating cellular responses through secretory vesicles.

This study demonstrates that human epidermal stem cells can adapt to environmental temperature changes through mTOR signaling, and prolonged inhibition of mTORC1 supports stem cell maintenance, which may be vital for regenerative medicine.

KLHL24-mutant stem cells help understand skin and heart disease.

Early-stage skin substitutes improve wound healing and skin structure.

In this study, researchers found that disrupting desmoglein 3 signaling in a mouse model of pemphigus vulgaris activates normally quiescent hair follicle stem cells, compromising their multipotency but prompting a regenerative response that restores stem cell function and structures.

This study found that super-enhancers in squamous cell carcinoma stem cells are distinctly different from those in normal skin stem cells, with ETS2 playing a crucial role in promoting tumor growth.

This review examines patents and publications on steroid sulfatase inhibitors since 1999 and reports no new clinical results, highlighting their potential for treating estrogen- and androgen-driven conditions.

In this study, researchers identified that three homologous genes—ZmSPL10, ZmSPL14, and ZmSPL26—are crucial for the development of stigmatic papilla in maize, with triple knockout mutants lacking these genes showing almost no stigmatic papilla and significantly reduced kernel setting.

This study used two-photon microscopy to reveal that the dermal papilla is crucial for hair follicle regeneration and cannot be replaced by neighboring cells, providing new insights into stem cell behavior.

This study suggests that human embryonic stem cells may improve skin graft quality and functionality by enabling the identification and amplification of early ectodermal progenitors, pending confirmation from preclinical studies.

This study suggests that the DORN1 receptor may play a role in eATP-induced changes in stomatal aperture in Arabidopsis thaliana, but not in the eADP signaling pathway.

This study discusses the rise of commercial direct-to-consumer stem cell therapies, highlighting how they are marketed as biomedical 'lifestyle' products that blend science, medicine, and consumer culture, despite ongoing safety and efficacy concerns.

This study found that stem cells from mouse dental pulp and vibrissae shared similar marker profiles, but dental pulp stem cells expressed a broader range of stem cell markers, suggesting their potential use in regenerative medicine.

This article reviews the role of stem cells in tissue development, tumor formation, and organoid generation, and highlights the potential of epigenetic regulation in advancing regenerative medicine and cancer treatment, without presenting new experimental results.

In this study, researchers used genomic, metabolomic, and transcriptomic methods to explore the biosynthetic capabilities of S. longa, aiming to better understand the species and lay the groundwork for future studies on the biosynthesis and therapeutic use of cepharanthine and similar alkaloids.

This review discusses various human skin equivalents, including those involving stem cells, and compares their structure and application, without presenting new clinical findings.

This study identified a comprehensive global landscape of stemness-related gene clusters in adipose-derived mesenchymal stem cells, revealing that stemness was highest in cells from young donors and lowest in those from elderly donors.

This study found that dietary serine levels influence hair follicle stem cells' ability to balance hair regeneration and wound repair, offering insights for potential interventions to accelerate wound healing.

This study demonstrates that hair follicle bulge stem cells can transition into other stem cell compartments, indicating their role in maintaining both hair follicles and sebaceous glands.

This study found that Wnt signalling activates hair follicle fate in hair follicle stem cells by relieving TCF3/4–TLE-mediated repression, with β-catenin being crucial for this process.

The researchers developed semi-dissolving microneedle patches using TEMPO-oxidized bacterial cellulose nanofibers, which allow effective transdermal drug delivery by forming micro-channels for large drug quantities, overcoming traditional microneedles' low drug loading.

This study found a previously unreported ST14 gene mutation in a patient with ichthyosis-hypotrichosis syndrome, highlighting novel skin and hair characteristics and emphasizing the critical role of the Asp482 amino acid in matriptase activation.

This study found that dendritic epidermal T cells and their exosomes enhance epidermal stem cell proliferation, accelerating wound re-epithelialization in the skin.

This study explored the secretion and cellular localization of different forms of follistatin and FST-like-3, revealing variable secretion kinetics and possible intracellular roles, particularly for nuclear FSTL3.

In this study, researchers isolated multipotent stem cells from elderly human epidermis and showed that they could differentiate into neurons using TAT-VHL peptide, suggesting potential for regenerative therapies.

This study developed immortalized human hair follicle-derived mesenchymal-like stromal cells (iHF-MSCs) as a consistent source of therapeutic secretome, reporting their superior immunomodulatory and regenerative performance, potentially advancing cell-free therapies for inflammation and tissue repair.

In this study with mice, simultaneous inactivation of Smad4 and PTEN genes led to rapid development of invasive forestomach squamous cell carcinomas, mirroring human esophageal SCCs.