September 2024 in “Journal of Cosmetic Dermatology” In this study, researchers found that Ectoin, derived from halophilic bacteria, can mitigate stress-related skin damage by reducing cortisone's inhibitory effects on essential skin proteins and decreasing UVB-induced glucocorticoid activity, highlighting its potential as a preventative agent for stress-induced skin issues.
July 2026 in “Future Journal of Pharmaceuticals and Health Sciences” This study explored the potential of Tridax procumbens, a medicinal plant, for hair growth applications by analyzing its bioactive compounds through in silico and phytopharmacological evaluations, resulting in a novel hair serum formulation that demonstrated promising hair growth-promoting properties in preliminary tests.
5 citations
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September 2018 in “Bioscience, Biotechnology, and Biochemistry” In this study, sodium thiosulfate was observed to promote hair growth in mice by encouraging hair follicles to enter the growth phase and complementing the effects of minoxidil, suggesting potential benefits for hair loss treatment.
34 citations
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April 2018 in “EMBO journal” This study found that in mouse skin, the activation of stem/progenitor cells is synchronized across different niches during growth, with the glutamate transporter SLC1A3 playing a crucial role in this process.
March 2023 in “International journal of pharmaceutical sciences review and research” In this study, an Emulgel containing Tridax procumbens extract was formulated and found to have promising physical properties and antimicrobial activity for wound healing.
In this study, researchers used the CRISPR/Cas9 system to edit the FGF5 gene in Dorper sheep, observing increased density and finer wool, along with changes in cortisol levels and antioxidant enzyme activity linked to hair follicle development.
291 citations
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April 2010 in “Gastroenterology” This study identified Lgr5 and Lgr6 as receptors expressed by small populations of stem cells in various adult organs, with Lgr5+ve cells forming long-lived organoids in certain mouse models.
August 2018 in “Analysis of the application of various variants of bone plasty in victims with intraarticular fractures (Transplantology)” In this study, follicular microautotransplantation was found to be an effective outpatient surgical treatment for scarring alopecia, with transplanted follicles showing an average engraftment rate of 93.8% and providing a good cosmetic outcome that improves patients' quality of life.
January 1980 in “Lluc: revista de cultura i d'idees” This study found that Agaricus bisporus-derived β-Glucan particles showed potential as an anticancer, antimicrobial, and antioxidant agent, inducing apoptosis and disrupting mitochondrial membrane potential in cervical cancer HeLa cells.
2 citations
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March 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that both bFGF and herbal extracts significantly induced proliferation in human hair follicle mesenchymal stem cells, suggesting their potential for promoting hair growth.
9 citations
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April 2024 in “The Oncologist” This study found that sacituzumab govitecan improved health-related quality of life in most areas for patients with HR+/HER2− metastatic breast cancer compared to chemotherapy, except for increased diarrhea, supporting its use as a treatment option.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a multipurpose herbal gel formulation that enhances hair manageability, provides antimicrobial benefits, and supports skin care. The gel is non-irritating, leaves hair soft, and imparts a glow to the skin while being cost-effective.
August 2023 in “Journal of controlled release” This research found that STAR particles, ceramic particles with microneedles, significantly enhance skin permeability and improve the topical delivery of drugs like minoxidil and acyclovir, effectively promoting or inhibiting hair growth without causing skin irritation in ex vivo pig skin and rat models.
3 citations
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March 2022 in “Polymers” This study found that applying glycosaminoglycans fractions from ascidian tunics stimulated human follicle dermal papilla cell proliferation and, when used on mice hair for 28 days, produced a hair growth effect comparable to Minoxidil.
3 citations
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December 2024 in “Journal of Animal Physiology and Animal Nutrition” In this study, researchers found that reducing FGF20 expression in dermal papilla cells of fine-wool sheep impedes the growth and differentiation of hair follicle stem cells, providing insights into wool trait improvement and regenerative medicine applications.
This study found that the 100% herbal complex extract, including Houttuynia cordata, significantly stimulated hair growth and increased hair density and weight in C57BL/6 mice, comparable to minoxidil treatment.
January 2023 in “Methods in molecular biology” This article reviews methods for examining the localization and activity of ROP GTPase, cortical microtubule organization, and F-actin dynamics in plant cell models, but reports no new experimental results.
HEM-13HDC, a mix of 8 herbal extracts, helps hair grow and affects hair growth at a molecular level.
February 2024 in “Journal of medicinal food” This study reports that the β-catenin inhibitor tegatrabetan reduced hair growth and hair follicle numbers in mice, suggesting its potential as a model for developing new hair growth materials.
This study introduces a new type of tissue micromodule, the micro tissue precursor (μTP), which can form complex 3D tissues, including lung stroma and skin models supporting hair viability.
1 citations
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January 1996 in “Aesthetic Plastic Surgery” This study suggests that the tumescent technique can improve hair micrografting by effectively providing anesthesia and reducing bleeding without the need for multiple needle injections or nerve blocks.
1 citations
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May 2019 in “International Journal of Applied Pharmaceutics” This study evaluated hair tonic and gel formulations containing Angiopteris evecta root water extract and found both fulfilled pharmaceutical preparation standards, with the 12.5% hair tonic and 10.0% gel concentrations most effective for hair growth without a significant difference in performance.
1 citations
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August 2022 in “BMC Plant Biology” Melatonin helps broccoli roots produce anti-cancer compounds by controlling nitric oxide and hydrogen peroxide levels.
October 2017 in “Journal of The European Academy of Dermatology and Venereology” Stem cells preservation in AGA could be a potential therapy, but more cases needed.
37 citations
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February 2005 in “Journal of Investigative Dermatology” This research suggests that defects in keratinocyte differentiation due to putrescine accumulation in SSAT transgenic mice lead to skin changes and hair loss, and reducing putrescine can promote hair regrowth.
3 citations
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September 2016 in “Natural Product Communications” This study identified 8-hydroxy germacrene B from Curcuma aeruginosa as a highly potent in-vitro 5-alpha reductase inhibitor with significant anti-androgenic activity, while exhibiting mild cytotoxicity on prostate cancer cells without affecting human dermal papilla cells at tested concentrations.
1 citations
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January 1983 in “Radboud Repository (Radboud University)”
1 citations
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March 2023 in “Science Translational Medicine” The researchers reported that targeting glycoprotein 130's signaling site in animal models promoted tissue regeneration and reduced osteoarthritis progression through anti-inflammatory and protective effects.
November 2025 in “International Journal of Innovative Research and Scientific Studies” This study found that Regenera ActivaAMT significantly improved hair growth and patient satisfaction in both men and women with Androgenetic Alopecia, suggesting it may be an effective alternative to hair transplants.
6 citations
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January 2016 in “Methods in molecular biology” This protocol describes a method for regenerating hair follicles using a bioengineering technique called the Organ Germ Method, but it reports no new clinical results.