3 citations
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October 2011 in “JAT. Journal of applied toxicology/Journal of applied toxicology” This study found that finasteride was nongenotoxic in Drosophila, while doxazosin mesylate and saw palmetto induced homologous recombination, indicating potential genotoxic actions under the test conditions.
June 2015 in “Reactions weekly” December 2012 in “Reactions weekly”
June 2021 in “Archives of Advances in Biosciences” This study suggests that finasteride at doses of 5 mg/kg BW or higher may adversely affect spermatogenesis and male fertility in NMRI mice.
July 2021 in “Asia-Pacific journal of convergent research interchange” This research on dermal papilla cells found that Sparasis crispa increased mRNA expression related to hair production and may help in hair generation cycles, but its impact on male hair loss treatment remains uncertain.
1 citations
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August 2019 in “Environmental Toxicology” This study observed that low-dose intrauterine exposure to finasteride alters postnatal prostate development in male and female Mongolian gerbils, showing sex-specific differences in receptor expression and tissue changes.
November 2020 in “International journal of pharmaceutical compounding” This study developed and tested a finasteride suspension that retains over 94.3% of its initial concentration for up to 90 days at room temperature, finding no airborne finasteride exposure during formulation handling.
This study observed that intrauterine and early postnatal exposure to finasteride affected prostatic development in Mongolian gerbils, with significant sex-based differences, particularly higher alterations in female prostates.
October 2012 in “Sax's Dangerous Properties of Industrial Materials”
14 citations
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March 2020 in “Cold Spring Harbor Perspectives in Biology” This review discusses the flexibility and diversity of tissue stem cell systems, particularly focusing on the motility and ligand distribution of spermatogenic stem cells, without presenting new experimental results.
57 citations
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July 2009 in “Urology” This study found that finasteride may decrease and control the frequency of priapism episodes in patients with sickle cell anemia, with fewer side effects compared to other treatments.
20 citations
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April 2012 in “Fertility and Sterility” In this laboratory study with rats, treatment with finasteride reduced dihydrotestosterone levels and fertility parameters, with a 30-day recovery period proving insufficient to fully restore sperm function and fertility.
49 citations
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December 2007 in “Fertility and Sterility” This case report describes two infertile patients who experienced significant improvements in sperm concentrations six months after stopping finasteride.
3 citations
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January 2010 in “Yearbook of Urology” January 2010 in “Yearbook of Urology”
June 2019 in “Reactions Weekly” 6 citations
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October 2015 in “Experimental dermatology” This study found that adenine supplementation in cultured human follicle dermal papilla cells stimulated proliferation and reduced senescence, possibly through AMPK activation and increased cellular NAD+ levels.
1 citations
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July 2021 in “Current Issues in Molecular Biology” This study found that finasteride treatment of male rats led to changes in their male offspring's testicular gene expression, potentially affecting sperm function in response to odorant-like signals.
January 2006 in “Analytical chemistry, an Indian journal” This study developed two sensitive spectrophotometric methods to accurately determine finasteride in pure and tablet forms, demonstrating linear response and compliance with ICH guidelines.
3 citations
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March 2022 in “Research journal of pharmacy and technology” This study found that the compound (+)–Marmesin from Petroselinum crispum showed potential as an anti-alopecia agent by demonstrating better binding to androgen receptors than minoxidil, though not surpassing native ligands.
May 2022 in “Endocrine Abstracts” Finasteride may cause sexual dysfunction by reducing epinephrine levels.
23 citations
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January 2007 in “Archives of Andrology” This study reported that semen quality improved in three young men after discontinuing long-term finasteride use, although meiotic abnormalities persisted.
36 citations
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June 2001 in “Neuroscience Letters” This study found that finasteride increased fetal arousal activity in late gestation sheep by suppressing pregnane steroid synthesis, suggesting reduced GABAA receptor-mediated inhibition.
3 citations
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March 2012 in “Arab Journal of Urology” This study found that cromakalim and pinacidil significantly inhibited porcine detrusor muscle contractions, suggesting these ATP-sensitive potassium channel openers may have potential in treating certain bladder diseases.
42 citations
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August 2012 in “Psychoneuroendocrinology” Finasteride reduces certain behaviors caused by D1-like receptor agonists but not by D2-like receptor agonists in mice.
January 2014 in “Reactions Weekly” June 2014 in “Reactions Weekly” May 2026 in “Reactions Weekly” April 2026 in “Reactions Weekly” December 2024 in “Reactions Weekly”