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This study found that zinc is primarily located in the tails of mature rat sperm, associated with -S-S-bonded structures, and suggests a possible similarity in zinc interactions between sperm keratin and hair proteins.

This case report suggests that discontinuing low-dose finasteride in a 48-year-old man led to a significant reduction in sperm DNA fragmentation index, indicating a possible link between finasteride and sperm DNA damage.

This study found that dual 5α-reductase inhibition in rats led to decreased sperm motility and altered morphology, resulting in subfertility.

This review discusses the risk factors and implications of sperm aneuploidy in males, and it reports no new clinical results; the authors highlight the importance of personalized assessment in assisted reproduction.

This study found that Origanum vulgare extract improved testicular structure and function in mice against finasteride-induced damage by enhancing antioxidant defense and modulating gene expression related to apoptosis.

This study reported a marginally lower sperm retrieval rate using micro-testicular sperm extraction (m-TESE) among nonmosaic Klinefelter Syndrome patients compared to existing literature, with younger patients benefitting more significantly from the procedure.

This study found that finasteride may affect Ca 2+ signalling in human sperm by interacting with the PGE 1 -binding site, but its impact on fertilization requires further investigation.

In this study, high doses of Lepidium sativum seeds extract were reported to cause toxicity and tissue damage in animals, suggesting the need for careful use under medical supervision.

This study found that a mild intramuscular dose of BOTOX increased spermatogenesis and improved sperm quality in ageing mice, suggesting potential benefits for managing male infertility.

This review reports an increasing trend in sperm DNA fragmentation research over the past 20 years, with a focus on lifestyle, asthenozoospermia, and varicocele, and highlights the TUNEL technique as widely used.

This analysis of seven studies explored the impact of finasteride (1mg/day for androgenic alopecia) on sperm concentration, finding that in most studies, sperm concentration increased after stopping treatment, but the largest study showed no change during or after treatment.

This study in Tehran found that, after adjusting for confounders, women with PCOS had no different risk of non-pregnancy after assisted reproductive treatment compared to women without PCOS.

In this study, autologous intratesticular PRP injection was found to be a feasible and well-tolerated procedure with low complication rates and quick recovery, but the authors indicated that current evidence is insufficient to confirm its effectiveness for mTESE.

This study confirmed that an injectable implant known as RISUG-PH™, when administered via the vas deferens, successfully delivers the drug Finasteride to the prostate in male rats for up to 28 days, suggesting a potential localized alternative to oral delivery methods.

Seminal bacteria can lower sperm quality in subfertile men.

In this study, researchers found that both the EU-TIRADS and Bethesda systems exhibited high specificity but suboptimal sensitivity for predicting thyroid nodule malignancy in patients who underwent surgery, with Bethesda system showing particularly high specificity in this postoperative population.

This review found an increasing trend in research on sperm DNA fragmentation over the past 20 years, especially focusing on lifestyle factors, asthenozoospermia, and varicocele, with the TUNEL technique as a predominant method.

This study observed that adult offspring of sperm donation generally feel positive about their conception method and believe identifying information about donors should be accessible.

This study found that stem cell transplantation effectively reduced acute inflammation-induced testicular damage, suggesting potential for cell-based therapies in addressing male infertility.

This study suggests that a mild intramuscular dose of botulinum toxin improved spermatogenesis and sperm parameters in ageing mice.

This review discusses recent research on male infertility causes and treatments, emphasizing the need for further understanding of idiopathic sperm abnormalities and molecular factors to improve patient outcomes; it reports no new clinical results.

This article reviews the effects of various medications on male fertility, noting that while commonly used drugs can mostly have reversible impacts, conclusive human evidence remains limited.

This article discusses the potential effects of exogenous testosterone, highlighting that its impact on prostate cancer progression, cardiovascular health, and behavior remains uncertain and needs further investigation.

This study describes a family with X-linked gynecomastia and undervirilization in men, finding a subtle androgen receptor abnormality that may not always lead to infertility despite androgen resistance.

This study found that discontinuing finasteride led to a significant increase in sperm counts for most men with reduced fertility, though hormone levels and other semen parameters remained unchanged.

This case report describes two infertile patients who experienced significant improvements in sperm concentrations six months after stopping finasteride.

This review assesses the current literature on COVID-19's effects on male sexual and reproductive health, highlighting significant research gaps and providing guidance for patient counseling.

In this study, the authors concluded that COVID-19 may not cause direct long-term harm to testicular function, but temporary indirect effects could occur, suggesting a possible delay in pursuing parenthood post-recovery.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.