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New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

A new genetic change in the keratin 10 gene caused a skin condition called ichthyosis hystrix in a father and his daughter.

Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Long-haul COVID can cause lasting symptoms affecting many body systems and may be linked to ongoing inflammation and immune system issues.

Targeting and modifying the stem cell niche can improve regenerative therapies.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

Lanceolate complexes in mouse hair follicles are essential for touch and depend on specific cells for maintenance and regeneration.

Targeting the Smoothened receptor shows promise for treating certain cancers.

New therapies are being developed that target integrin pathways to treat various diseases.

Noggin gene inactivation causes skeletal defects in mice, varying by genetic background.

Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.

New hair growth corticosterone levels are higher in diabetic mice, indicating long-term stress.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Tiny vesicles from stem cells could be a new treatment for healing wounds.

The model accurately predicts age from saliva and buccal cells for forensic use.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

New targeted immunotherapies are improving treatment for inflammatory skin diseases.

Men and women get COVID-19 at similar rates, but men tend to get sicker and have a higher risk of dying, while women usually have stronger immune responses and vaccine reactions.

Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

Scientists successfully edited a goat's genes to grow more and longer cashmere hair.

Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.

SOX9 is essential for the development of various organs and hair follicles.

Adding a second method to PROTACs could improve cancer treatment.

DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.

Patients with long COVID after Omicron had fewer hospitalizations and milder symptoms but more fatigue, insomnia, and cough compared to those with Delta.

The research found genes that change during cashmere goat hair growth and could help determine the best time to harvest cashmere.