61 citations,
October 2011 in “Experimental dermatology” Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.
49 citations,
June 2019 in “eLife” Ancient DNA blocks are still present in human genomes, possibly due to advantages they provide.
45 citations,
October 2008 in “Cytokine & Growth Factor Reviews” Activins and follistatins, part of the TGFβ family, are crucial for hair follicle development and skin health, affecting growth, repair, and the hair cycle.
41 citations,
March 2019 in “Circulation research” Adult stem cells are effective and ethically acceptable for treating various diseases.
34 citations,
January 2013 in “Frontiers in genetics” Stem cells can help other stem cells by producing supportive factors.
31 citations,
August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
24 citations,
November 2023 in “Nature” The extracellular matrix affects where tumors can start in the body.
23 citations,
May 2019 in “Stem cell research & therapy” iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.
23 citations,
January 2014 in “Evidence-based Complementary and Alternative Medicine” Mushroom beta-glucans from Ganoderma lucidum can reduce tumor size and metastasis in cancer.
22 citations,
January 1985 in “Journal of Human Evolution/Journal of human evolution” Human skin and hair color variation is mainly due to melanin produced by a few genes, with melanin protecting against sun damage.
15 citations,
January 2015 in “Stem cells international” Human hair follicle stem cells can be turned into red blood cells.
11 citations,
February 2019 in “Stem cells international” Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.
11 citations,
April 2013 in “Homo” Darker skin in 10-year-old girls may be an early sign of puberty.
9 citations,
February 2021 in “Frontiers in Cell and Developmental Biology” Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
9 citations,
May 2002 in “PubMed” Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.
8 citations,
June 2022 in “Scientific Reports” LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.
8 citations,
July 2015 in “Molecular cytogenetics” A complex X chromosome rearrangement can increase the risk of multiple autoimmune diseases.
7 citations,
June 2020 in “npj regenerative medicine” GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
7 citations,
September 2013 in “Familial cancer” Birt–Hogg–Dubé syndrome is a rare genetic condition causing skin lesions, lung cysts, and a higher chance of kidney cancer.
4 citations,
August 2021 in “Clinics in Dermatology” Stem cells show promise for hair loss and skin treatments in aesthetics but need more research on safety and standard methods.
3 citations,
June 2022 in “Cells” The conclusion is that the new method makes collecting cells from plucked hair to create stem cells more efficient and less invasive.
3 citations,
August 2018 in “Stem cells international” Hair follicle cells help maintain and support stem cells and blood cell formation.
2 citations,
October 2022 in “Journal of Biomedical Science” Stem cells and their secretions could potentially treat stress-induced hair loss, but more human trials are needed.
2 citations,
May 2021 in “International journal of molecular sciences” Stem cells from hair follicles in a special gel show strong potential for bone regeneration.
2 citations,
January 2021 in “Scandinavian Journal of Child and Adolescent Psychiatry and Psychology” Kids with skin problems are more likely to have mental health issues.
August 2024 in “Archives of Dermatological Research” Certain genetic variants and pathways are linked to hair loss.
May 2023 in “Frontiers in Cell and Developmental Biology” The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.
April 2023 in “Bulletin of the National Research Centre” The document concludes that more research is needed to understand how PRP affects the ovaries and to standardize its use in treatment.
March 2023 in “JAAD case reports” A new genetic change in the keratin 10 gene caused a skin condition called ichthyosis hystrix in a father and his daughter.
November 2022 in “Journal of Investigative Dermatology” Some people with schwannomatosis have a new type of mutation in the LZTR1 gene.