Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study identified overexpression of certain immune-related genes and underexpression of genes in specific signaling pathways in premature androgenetic alopecia, suggesting potential new therapeutic targets.

This study found that 7.9% of dermatological outpatients at a German hospital had clinically relevant body dysmorphic concerns, highlighting the need for psychotherapeutic support due to poor social adaptation and high motivation for change.

This study found significant differences in the spread of sebum on hair among Chinese men with greasy and non-greasy scalps, despite similar sebum amounts at the root region post-shampoo.

This study found that Camellia japonica seed extract promotes hair growth by preventing premature cellular senescence and enhancing the activity of hair follicle stem cells in cases of pattern hair loss.

This ex vivo study found that hair follicles in female pattern hair loss exhibited nutrient insufficiency and dormant metabolism, but maintained nutrient uptake capability, suggesting potential benefits of nutritional supplementation as an adjunct therapy.

This review discusses the potential impact of endocrine-disrupting chemicals and body size on pubertal onset and progression, highlighting critical gaps and priorities for future research without presenting new clinical results.

This review found that the clinical results of L-PRF as a grafting material in maxillary sinus augmentation were mixed, with some studies reporting positive effects and others finding no significant impact.

This study found that a testosterone patch and gel showed bioequivalent testosterone levels in hypogonadal men, but the patch mimicked a natural circadian profile, while the gel resulted in higher dihydrotestosterone levels.

This article reviews the role of 5α-reductase in cutaneous hyperandrogenism and the potential of 5α-reductase inhibitors and antiandrogens in treating conditions like hirsutism and male-pattern baldness, reporting no clinical results.

In this study, the combination of arsenic toxicity and hypoxia in Arabidopsis thaliana altered root development through stress-specific root growth phenotypes and changes in phosphate starvation response, energy metabolism, and redox signaling.

This review found no evidence that DHEA improves quality of life or decreases menopausal symptoms in peri- and postmenopausal women, but it may slightly enhance sexual function compared to placebo.

This review discusses the enhanced permeability and retention (EPR) effect as a mechanism for targeted drug delivery in cancer therapy and reports no new clinical results.

This study found that using autologous adipose-derived stromal vascular fraction enriched with platelet-rich plasma may improve healing rates in patients undergoing flap repair for transsphincteric cryptoglandular fistulas.

This study demonstrated that in live rodents, actin filaments adjust their structure to facilitate membrane transfer between cellular compartments with different biophysical properties.

This study found that the extracts of Serenoa repens, when evaluated through chemical, biological, and in silico methods, demonstrated anti-inflammatory, pro-apoptotic, and anti-androgenic activities against prostate cancer cell lines, suggesting potential therapeutic benefits and directing future pharmaceutical development.

This article reviews the symptoms, diagnosis, and management of polycystic ovary syndrome, emphasizing lifestyle changes and medical interventions, but presents no new findings.

This study found that patients with Bachmann-Bupp syndrome treated with DFMO showed improvements in hair growth, muscle tone, and development.

This study found that testosterone therapy improved physical performance and strength in older men with low testosterone over 36 months, whether administered alone or with finasteride.

This review discusses idiopathic hirsutism, potential underlying mechanisms, and various therapeutic approaches without providing new clinical results, and emphasizes the need for further research on well-defined patient groups.

This review discusses the preclinical and clinical data on teriflunomide for multiple sclerosis, highlighting its selective action on immune cells without causing clinical immune suppression, and provides no new clinical results.

This review discusses the physiological roles of ovarian androgens in follicle development and atresia, emphasizing their contributions to polycystic ovary syndrome and normal follicle maturation but provides no new clinical results.

This study observed that nuclear β-catenin expression in non-small-cell lung carcinomas correlates with increased proliferation and loss of key cell-cycle checkpoints, suggesting an oncogenic advantage.

This review discusses the use of contact sensitizers for topical immunotherapy in dermatological conditions such as alopecia areata and viral warts, but it reports no new clinical findings.

This review highlights the promising potential of microemulsions and nanoemulsions in (trans)dermal drug delivery, noting a gap in understanding their distinct mechanisms and composition-related effects on skin permeability, while emphasizing the limited clarity on mesostructures and cosolvent impacts.

In this review, researchers discussed recent insights into caspases, enzymes initially associated with cell death and inflammation, revealing their broader roles in cell proliferation, migration, and differentiation, and highlighting the importance of caspase knock-out mice for understanding their implications in diseases.

This review evaluates laboratory models used in androgenetic alopecia research but reports no new findings, emphasizing the potential of human-derived 3-D models for future studies.

This study developed a method to quantify hair loss in mice, aiding the evaluation of new treatments for alopecia.

This study found that rice bran supercritical CO₂ extract was classified as a non-irritant for ocular use but a moderate irritant for dermal use in rabbits and guinea pigs.

This review discusses the applications of low level laser therapy (LLLT) in wound healing, pain reduction, and treating various conditions, but reports no new clinical results; the authors highlight the need for randomized controlled trials for serious diseases.

This review summarizes the roles of Wnt signaling in wound healing but presents no new clinical findings, suggesting potential for Wnt-based therapies to enhance tissue regeneration.