research Activation of TRPV3 Regulates Inflammatory Actions of Human Epidermal Keratinocytes
TRPV3 in skin cells causes inflammation and cell death.
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330-360 / 1000+ resultsresearch Structural Mechanism of TRPV3 Channel Inhibition by the Plant-Derived Coumarin Osthole
Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.
research Penetration of Different Molecular Weight Hydrolysed Keratins into Hair Fibres and Their Effects on the Physical Properties of Textured Hair
Different sizes of keratin peptides can strengthen hair, with smaller ones possibly increasing volume and larger ones repairing damage.
research Inhibitory Effects of the ATP-Sensitive Potassium Channel Openers Cromakalim, Pinacidil, and Minoxidil on the Carbachol-Response Curve in Porcine Detrusor Muscle
Certain drugs can reduce bladder muscle contractions, potentially helping treat bladder diseases.
research Synthesis and Evaluation of Finasteride-Loaded HPMC-Based Nanogels for Transdermal Delivery: A Versatile Nanoscopic Platform
Finasteride-loaded nanogels are effective, safe, and improve drug absorption through the skin.
research CBL1-CIPK26-Mediated Phosphorylation Enhances Activity of the NADPH Oxidase RBOHC, but Is Dispensable for Root Hair Growth
A specific protein complex increases the activity of a plant enzyme, but this action is not required for plant root hair growth.
research Different Ligands of the TRPV3 Cation Channel Cause Distinct Conformational Changes as Revealed by Intrinsic Tryptophan Fluorescence Quenching
Different ligands change the shape of the TRPV3 ion channel in unique ways.
research The Role of Candidate Pharmacogenetic Variants in Determining Valproic Acid Efficacy, Toxicity, and Concentrations in Patients with Epilepsy
Genetic variants can affect valproic acid's effectiveness, side effects, and levels in epilepsy treatment.
research An Overview of Incidence and Mechanisms Promoting Weight Gain as an Adverse Effect of Oral Minoxidil Therapy for Androgenetic Alopecia
Oral minoxidil for hair loss can cause weight gain due to fluid retention.
research Application of Validated UV Spectrophotometric and Colorimetric Method to Quantify Minoxidil in the Development of Trilayer Dissolving Microneedle: Proof of Concept in Ex Vivo and In Vivo Studies in Rats
The UV–Vis Spectrophotometry method effectively measures minoxidil in rat skin for alopecia treatment.
research The Role of EAAT4 in Epidermal Differentiation and Calcium Homeostasis During Aging
EAAT4 decreases with age, harming skin function and calcium balance.
research Efficacy of Derinat as a Treatment for Murine and Androgenetic Alopecia Patients
Derinat may improve hair growth and quality of life in hair loss patients by reducing oxidative stress.
research New Target for Minoxidil in the Treatment of Androgenetic Alopecia
Minoxidil may work for hair loss by reducing androgen sensitivity and altering hormone-related enzymes.
research Dissolving Microneedles: Applications and Growing Therapeutic Potential
Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
research Smart Microneedles for Therapy and Diagnosis
Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.
research Mechanisms of Action of Dehydroepiandrosterone
DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.
research Potassium Channel Openers Increase Aortic Elastic Fiber Formation and Reverse the Genetically Determined Elastin Deficit in the Brown Norway Rat
Potassium channel openers help form elastic fibers in arteries and can treat elastin deficiency and hypertension.
research Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes
A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.
research Combined Drug Triads for Synergistic Neuroprotection in Retinal Degeneration
Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.
research Hormonal Control of Vas Deferens Fluid Volume and Aquaporin Expression in Rats
Testosterone increases fluid secretion and aquaporin expression in the vas deferens, which is important for male fertility.
research CFTR Potentiator Ivacaftor Protects Against Noise-Induced Hair Cell Loss by Increasing Nrf2 and Reducing Oxidative Stress
Ivacaftor can protect against noise-induced hearing loss by reducing oxidative stress.
research Evaluation of Efficacy of Silybum Marianum Flower Extract on Mitigating Hair Loss In Vitro and In Vivo
Silybum marianum flower extract may help increase hair growth and decrease hair loss.
research Effects of a Combination of Arginine Silicate Inositol Complex and a Novel Form of Biotin on Hair and Nail Growth in a Rodent Model
The combination of Arginine Silicate Inositol Complex and a new form of Biotin improved hair and nail growth in rats.
research Retinal Artery Occlusion as a Probable Idiosyncratic Reaction to Topical Minoxidil: A Case Report
Using minoxidil for hair loss might cause sudden vision loss, so use it with caution and monitor closely.
research Role of Low Dose Oral Minoxidil in the Treatment of Hair Loss: A Review
Low-dose oral minoxidil is effective and well-tolerated for treating hair loss.
research Novel Natural Lipids Based NLC Containing Finasteride Improved Androgenetic Alopecia Treatment in Rats
Finasteride in lipid carriers improved hair growth in rats.
research Delivery of Minoxidil Encapsulated in Cyclodextrins with Photoacoustic Waves Enhances Hair Growth
Using photoacoustic waves to deliver minoxidil improves hair growth effectively and safely.
research Fractional CO2 Laser, Platelet Rich Plasma and Combination of Both in Treatment of Female Pattern Hair Loss
Combining fractional CO2 laser and PRP is very effective for treating female hair loss.
research Recent Advances in Microneedling-Assisted Cosmetic Applications
Microneedling improves skin and hair conditions by enhancing treatment absorption and stimulating growth factors.
research Topical Gabapentin and Its Relation to Cutaneous Innervation in Symptomatic Lymphocytic Primary Cicatricial Alopecia
Using a special skin cream with gabapentin helped reduce symptoms of a certain scalp condition but didn't change nerve fibers or skin chemicals.