An Overview of Incidence and Mechanisms Promoting Weight Gain as an Adverse Effect of Oral Minoxidil Therapy for Androgenetic Alopecia

    June 2024 in “ European Journal of Clinical and Experimental Medicine ”
    Łukasz Ciulkiewicz, Maciej Pełka, Justyna Fijałkowska, Anna Kania
    Image of study
    TLDR Oral minoxidil for hair loss can cause weight gain due to fluid retention.
    Oral minoxidil, used to treat androgenetic alopecia, can cause fluid retention leading to weight gain, with incidence rates varying from 0.22% to 10% across studies. The severity and frequency of this side effect are dose-dependent, and in some cases, rapid weight gain necessitates the addition of a diuretic or discontinuation of the treatment. The underlying mechanism involves alterations in the neurohumoral system and renal hemodynamics. Despite these side effects, oral minoxidil remains a generally safe and effective treatment for most patients. Further research is needed to fully understand the mechanisms and dose dependence of this adverse effect.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community How many of you have significant others?

      in Shaved/buzzed  105 upvotes 1 year ago
      The conversation revolves around the experiences of different individuals with hair loss treatments like Minoxidil, Finasteride, and RU58841. The discussion includes various perspectives on the effects of these treatments, the importance of hair for self-esteem and attractiveness, and the influence of significant others on the decision to use or stop using these treatments.

      community Comparison of options: topical vs medication

      in Female  1 upvotes 5 months ago
      A user diagnosed with AGA is seeking advice on hair loss treatments, comparing topical Minoxidil, Spironolactone, and Finasteride to oral medications and natural methods like dermastamping, PRP, and LED light. They are concerned about side effects and effectiveness, especially given their existing fatigue.

      community Why is Kevin Mann (Haircafe) Hated?

      in Chat  62 upvotes 1 year ago
      Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.

      community HMI 115 Phase 2 - Leaked pics from Discord

      in Research/Science  361 upvotes 6 months ago
      The conversation discusses HMI 115, a new hair loss treatment with promising results, showing a significant increase in hair density after two months. Some users are skeptical, while others are hopeful for its release and potential affordability.

    Related Research

    9 / 9 results