1 citations
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January 2018 in “Side effects of drugs annual” This review in SEDA Volume 40 summarizes new adverse reaction data for diuretics published in 2017, highlighting specific risks such as fractures with loop diuretics and hyperkalemia with spironolactone.
1 citations
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September 2017 in “Elsevier eBooks” Diuretics help the body get rid of excess salt and water by acting on the kidneys in different ways.
10 citations
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December 2009 in “Journal of the American Geriatrics Society” This case report discusses an 80-year-old man whose hyponatremia likely resulted from multiple causes, including diuretic use, excessive water intake, and urinary retention, emphasizing cautious management in older adults.
December 2010 in “Journal of the American Geriatrics Society” This article highlights the complexity of diagnosing hyponatremia in older adults, emphasizing the need to evaluate urinary tract obstruction, medication effects, and age-related changes rather than relying solely on spot urinary values.
11 citations
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October 2019 in “Cancers” This study found that spironolactone enhanced the effectiveness of non-DNA-damaging cancer drugs gemcitabine and osimertinib in cancer cell lines and a mouse xenograft model, likely by suppressing the anti-apoptotic protein survivin.