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Alopecia areata is a reversible, autoimmune-related hair loss that can have significant emotional impact and uncertain treatment effectiveness.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Special fiber materials boost the healing properties of certain stem cells.

Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.

Telocytes might help with skin repair and regeneration.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Fat cells in the skin help start healing and form important repair cells after injury.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.

EVAL membranes help create cell structures that can regrow hair follicles.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Dermal papilla cells help wounds heal better and can potentially grow new hair.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.