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Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.

Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Dermatologists need to understand hair products to treat hair and scalp issues better.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

One minoxidil-sensitive potassium channel exists in human hair follicles.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Platelet-rich plasma might help tissue regeneration in dentistry, but results vary and more research is needed.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Muscles and nerves that cause goosebumps also help control hair growth.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Stem cell niches are adaptable and key for tissue maintenance and repair.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.