3 citations,
January 2021 in “Plastic and Aesthetic Research” Hair loss reduces hair thickness and coverage, but drug treatments mainly revive dormant hairs rather than reverse thinning; patients often undervalue their hair loss severity.
31 citations,
November 2015 in “PloS one” Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.
May 2024 in “Journal of Cosmetic and Laser Therapy” Injectable platelet-rich fibrin improves hair growth and reduces hair loss in women.
1 citations,
September 2021 in “Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria” Androgenetic alopecia is common in South-West Nigeria, affecting more men than women, with stress worsening the condition.
6 citations,
June 2021 in “EClinicalMedicine” ALRV5XR significantly improves hair density in women with hair loss and is well-tolerated.
May 2024 in “Dermatologic therapy” AKN is a chronic scalp condition in African-descended males, treated with topicals, antibiotics, steroids, and sometimes surgery or laser.
January 2023 in “Journal of surgery and research” New treatment effectively reverses hair thinning in most patients with mild side effects.
Kerascalp hair serum was found to be safe and effective in improving hair growth and strength in people with mild to moderate hair loss.
5 citations,
October 2017 in “JOGC/Journal of obstetrics and gynaecology Canada” The conclusion is that proper diagnosis and long-term treatment, including medication, hair removal, and lifestyle changes, are important for improving hirsutism, especially in PCOS patients.
March 2024 in “BMC cancer” High levels of ST14 and TMEFF1 proteins in ovarian cancer are linked to worse patient outcomes and may be a new treatment target.
36 citations,
October 2021 in “Frontiers in Endocrinology” Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.
3 citations,
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
1 citations,
August 2023 in “The Journal of Pathology” Different types of skin fibroblasts have unique roles in skin health and disease.
124 citations,
December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
November 2023 in “npj regenerative medicine” Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
28 citations,
September 2015 in “Wiener Klinische Wochenschrift” New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The article concludes that creating a detailed map of normal human skin at the single-cell level is important.
33 citations,
September 2016 in “British journal of dermatology/British journal of dermatology, Supplement” Human hair follicle dermal cells can effectively replace other cells in engineered skin.
65 citations,
May 2017 in “Advances in wound care” Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.
1 citations,
December 2023 in “Biomaterials advances” Sponges made of soy protein and β-chitin with human cells from hair or fat can speed up healing of chronic wounds.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
8 citations,
January 2022 in “Burns and trauma” Skin cell-derived vesicles can help heal skin injuries effectively.
April 2018 in “Journal of Investigative Dermatology” High amphiregulin in the skin is a bad sign for acute graft-versus-host disease.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
73 citations,
August 2011 in “Stem Cell Research” Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.
42 citations,
August 1999 in “The American journal of pathology” Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.
24 citations,
November 2008 in “Arquivos Brasileiros de Endocrinologia & Metabologia” Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.
October 2023 in “International Journal of Cosmetic Science” WS Biotin, a new form of D-Biotin, improves water solubility and shows potential for hair and skin care without being toxic at low levels.
277 citations,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
202 citations,
August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.