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Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Applying a special compound can promote hair growth without harmful side effects.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Melatonin, the sleep hormone, can help treat skin conditions like dermatitis, hyperpigmentation, and scalp disorders, and may also aid in skin aging prevention and regeneration. However, it's not recommended for asthma due to its pro-inflammatory effect.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

Infrared radiation can cause skin aging and cancer at high temperatures but may have therapeutic benefits at controlled levels.

The book explains the science of tissue repair and regeneration, its medical uses, challenges, and ethical concerns.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.

Overexpressing SSAT enzyme reduces prostate tumor growth in mice.

Intralesional therapy for keratoacanthoma is effective and has fewer side effects than systemic treatments.

Rosemary may help treat various skin conditions due to its antioxidant and anti-inflammatory properties.

Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.

The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.

Krt15+ cells in the mouse intestine resist radiation and can start tumors.

The new wound dressing helps skin heal faster and fights infection.

The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.

Key genes linked to hair growth and cancer were identified in hairless mice.

ING5 is crucial for stem cell maintenance and preventing certain cancers.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Too much thymosin beta4 causes weird teeth and more hair growth in mice.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

Eating isoflavone can help mice grow hair by increasing a growth factor.

Mustard gas exposure causes hair loss, but treating with N-acetylcysteine can prevent it.

Septin4 helps kill colon cancer cells by working with the protein BAX.

The study found that stem cells and neutrophils are important for regenerating hair follicle structures in mice.