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Chemotherapy drugs can cause abnormal growth and changes in healthy skin and gland cells.

The scalp's microorganisms significantly affect hair health and disease.

The circadian clock plays a key role in hair growth and its disruption can affect hair regeneration.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.

The document concludes that both internal stem cell factors and external influences like the environment and hormones affect hair loss and aging, with potential treatments focusing on these areas.

Epithelial stem cells can adapt and help in tissue repair and regeneration.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.

Injecting alpha-melanocyte-stimulating hormone in mice improved skin healing and reduced scarring.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.

Vitamin D is crucial for skin health and managing skin diseases.

Frizzled 3 and Frizzled 6 together control the orientation of mouse hair follicles.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

KGF and activin are crucial for skin healing and repair.

Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.

Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.

Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.

Platelet-Rich Fibrin (PRF) can speed up healing in chronic wounds, improve hair density, and act as a natural filler for skin rejuvenation, but its use in hair loss treatment needs more evaluation.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

Aging in hair follicle stem cells leads to hair graying, thinning, and loss.

Understanding skin structure and development helps diagnose and treat skin disorders.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

Better hair loss models needed for research.

Hypothyroidism harms rat skin, but topical triiodothyronine may help improve it.

Glycogen metabolism is important for energy and processes in human hair follicles, and hair follicles may produce glucose from lactate.