research HDAC6-Dependent Deacetylation of NGF Dictates Its Ubiquitination and Maintains Primordial Follicle Dormancy
HDAC6 helps keep ovarian follicles dormant, extending female fertility.
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research PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis
Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.
research Drug Repurposing: Hypothesis, Molecular Aspects, and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
research Topical L-Thyroxine: The Cinderella Among Hormones Waiting to Dance on the Floor of Dermatological Therapy?
Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Protein Degradation: Expanding the Toolbox to Restrain Cancer Drug Resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
research Epidermal Stem Cells in Wound Healing and Their Clinical Applications
Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
research A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells
The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
research Nigella Sativa And Its Nano-Mediated Approach Toward Management Of Neurodegenerative Disorders: A Review
Black cumin and its nanoformulations show promise in treating neurodegenerative diseases.
research Transcranial Photobiomodulation for Brain Diseases: Review of Animal and Human Studies Including Mechanisms and Emerging Trends
Light therapy on the brain shows promise for treating brain diseases and improving brain function.
research Sirtuins Pathways and Redox Homeostasis: A Pilot Study on Young and Old Monozygotic Twins
The study suggests that higher levels of SIRT1 and SIRT2 may improve overall cell health and aging processes.
research Changes in the Aging Dermal Hair Follicle Environment in Female Scalp
Aging causes changes in scalp cells that can negatively affect hair health.
research Redox-Directed Interventions Targeting Skin Photodamage
Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.
research Investigation of the Crosstalk Between Proteasome Function and Nucleotide Excision Repair Mechanism During Aging
The document concludes that the discussed biological mechanisms and potential therapies are not related to hair loss or hair growth.
research MiR-29 Is an Important Driver of Aging-Related Phenotypes
miR-29 is a key factor that accelerates aging.
research Comparison of Three Different Lactic Acid Bacteria-Fermented Proteins on RAW 264.7 Osteoclast and MC3T3-E1 Osteoblast Differentiation
Fermented soy protein may help prevent bone loss by affecting bone cell activity.
research Human Scalp Skin as an Abundant and Accessible Source for Eccrine Sweat Gland Isolation and Organ Culture
Researchers found a new way to isolate sweat glands from the scalp for study and culture.
research Melatonin Membrane Receptors in Peripheral Tissues: Distribution and Functions
Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
research Analysis of lncRNAs Expression Profiles in Hair Follicles of Hu Sheep Lambskin
lncRNAs may regulate hair follicle development in Hu sheep.
research Calcium Regulation of Stem Cells
Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
research Screening the Key Genes of Hair Follicle Growth Cycle in Inner Mongolian Cashmere Goat Based on RNA Sequencing
Researchers identified genes that may affect hair growth in Cashmere goats.
research Post-Acute COVID-19 Sequelae – 'COVID Long Hauler'
Long COVID causes lasting symptoms and needs ongoing care.
research V Congress of the Portuguese Society of Cosmetological Sciences - Proceedings
The congress showed advancements in skin hydration, barrier function, and safe, effective new cosmetic formulations.
research The Importance of Biomedical Engineers in the Health System
Biomedical engineers are crucial for developing better treatments for chronic and autoimmune diseases.
research Hopes and Limits of Adipose-Derived Stem Cells and Mesenchymal Stem Cells in Wound Healing
ADSCs help in wound healing and skin regeneration but need more research for full understanding.
research Retracted Article: Up-Regulated lncRNA5322 Elevates MAPK1 to Enhance Proliferation of Hair Follicle Stem Cells as a ceRNA of microRNA-19b-3p
A specific RNA increases hair stem cell growth and skin healing by affecting a protein through interaction with a microRNA.
research Dermatologic Manifestations of Mitochondrial Dysfunction: A Review of the Literature
Mitochondrial dysfunction is linked to various skin conditions and could be a target for treatments.
research Clock Genes, Hair Growth, and Aging
Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.
research The Dark and the Bright Sides of the Transcription Factor Nrf2 in Skin Protection and Disease
Nrf2 helps protect skin from damage but too much can cause skin problems.