32 citations,
April 2016 in “Journal of Investigative Dermatology” STAT5 activation is crucial for starting the hair growth phase.
31 citations,
April 2016 in “Nature communications” Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
30 citations,
January 2009 in “Nuclear Receptor Signaling” Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.
27 citations,
November 2013 in “Journal of Dermatological Science” The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.
22 citations,
December 2013 in “Molecular biology of the cell” ILK is essential for proper hair follicle development and structure.
20 citations,
September 2010 in “Cell Cycle” Mice can regenerate ear tissue without the p53 protein.
18 citations,
April 2014 in “Stem cells” The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.
10 citations,
October 2020 in “Frontiers in Cell and Developmental Biology” Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
9 citations,
November 2020 in “The FASEB journal” Intermediate filaments are crucial for cell differentiation and stem cell function.
9 citations,
April 2019 in “Bioscience, biotechnology, and biochemistry” Ten miRNAs may play key roles in starting secondary hair follicle development in sheep foetuses.
8 citations,
February 2013 in “Central European Journal of Biology” Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
5 citations,
May 2019 in “Archives of Dermatological Research” Narrowband UVB treatment increases certain gene expressions in psoriasis skin and improves symptoms.
5 citations,
August 2013 in “InTech eBooks” KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
4 citations,
November 2022 in “Frontiers in endocrinology” The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.
4 citations,
April 2021 in “Frontiers in Immunology” Different types of RNAs are found in varying amounts in patients with Polycystic Ovary Syndrome, suggesting they could be important in the disease's development and potentially used as disease markers.
3 citations,
April 2011 in “Expert Review of Dermatology” Male hair loss is caused by inactive hair follicle stem cells.
1 citations,
January 2017 in “Springer eBooks” Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.
January 2024 in “Pharmacy information” New treatments using stem cells and other methods show promise for promoting hair growth in androgenetic alopecia.
November 2023 in “npj regenerative medicine” Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
March 2021 in “Research Square (Research Square)” The SbbHLH85 protein helps sweet sorghum grow more root hairs but makes the plant more sensitive to salt.
September 2017 in “Korean journal of acupuncture” Crataegi Fructus water extract helps hair grow better and thicker.
266 citations,
January 2016 in “Development” YAP and TAZ are crucial for skin cell growth and repair.
101 citations,
March 2019 in “Cell Stem Cell” Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
52 citations,
September 2018 in “International Journal of Molecular Sciences” Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.
34 citations,
June 2008 in “In vitro cellular & developmental biology. Animal” Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.
24 citations,
October 2016 in “Oncotarget” Finasteride has a higher risk of reproductive side effects than minoxidil.
11 citations,
February 2018 in “Oncotarget” Lower SMAD2/3 activation predicts more severe skin cancer.
9 citations,
May 2012 in “PLOS ONE” ILK is essential for skin development, pigmentation, and healing.
October 2024 in “Current Issues in Molecular Biology” Platycladus orientalis leaf extract helps hair grow by activating certain proteins.
April 2024 in “International journal of molecular sciences” Alopecia areata and vitiligo share immune system dysfunction but differ in specific immune responses and affected areas.