research Roles of the Hedgehog Signaling Pathway in Cutaneous Physiology and Oncology
The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.
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900-930 / 1000+ resultsresearch Modulating Aging and Aging-Related Symptoms Using Endogenous Small Molecules
A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.
research Epidermal Wnt/Beta-Catenin Signaling Promotes Dermal Adipocyte Differentiation During Hair Follicle Morphogenesis and Regeneration
Wnt/beta-catenin signaling in the skin helps fat cell development during hair growth and repair.
research Wnt1/β-Catenin Injury Response Activates the Epicardium and Cardiac Fibroblasts to Promote Cardiac Repair
Wnt1/βcatenin signaling is crucial for heart repair after injury.
research Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells
Baricitinib reduces inflammation and improves cell health in premature aging cells.
research Functional Characterization of Soybean Strigolactone Biosynthesis and Signaling Genes in Arabidopsis MAX Mutants and GmMAX3 in Soybean Nodulation
GmMAX3b gene in soybeans boosts nodulation and affects hormone levels.
research Human Epithelial Stem Cell Survival Within Their Niche Requires Tonic Cannabinoid Receptor 1 Signaling—Lessons From the Hair Follicle
Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.
research Phytochemical Studies on Traditional Herbal Medicines Based on Ethnopharmacological Information Obtained by Field Studies
Over 150 new molecules with biological activities were found in traditional herbal medicines, some with potential for new drug development.
research Myristoleic Acid Promotes Anagen Signaling by Autophagy Through Activating Wnt/β-Catenin and ERK Pathways in Dermal Papilla Cells
Myristoleic acid helps hair growth by boosting cell growth and recycling processes in hair follicle cells.
research WWOX Deficiency Causes Downregulation of Prosurvival ERK Signaling and Abnormal Homeostatic Responses in Mouse Skin
WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
research Commensal Microbiome Promotes Hair Follicle Regeneration by Inducing Keratinocyte HIF-1α Signaling and Glutamine Metabolism
The skin's microbiome helps hair regrow by boosting certain cell signals and metabolism.
research Treatment with Malva Verticillata Seed Extracts Alleviates Alopecia via Activation of Wnt/β-Catenin Signaling
Malva verticillata seed extracts, specifically linoleic acid, can help reduce hair loss and promote hair growth by activating certain cell signals.
research Hair Thickness Growth Effect of Adenosine Complex in Male and Female Patterned Hair Loss via Inhibition of Androgen Receptor Signaling
Adenosine complex helps increase hair thickness and density in hair loss.
research Cold Atmospheric Microwave Plasma Stimulates Dermal Papilla Cell Proliferation by Inducing Beta-Catenin Signaling
Cold Atmospheric Microwave Plasma (CAMP) helps hair cells grow and could potentially treat hair loss.
research Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts
Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.
research Identification of Key Genes and Signaling Pathways Related to Hetian Sheep Wool Density by RNA-Seq Technology
Certain genes and pathways are linked to the production of finer and denser wool in Hetian sheep.
research Water Extract of Cacumen Platycladi Promotes Hair Growth Through the Akt/GSK3β/β-Catenin Signaling Pathway
Water extract of Cacumen Platycladi helps hair growth by activating specific cell pathways.
research Mapping the Molecular and Structural Specialization of the Skin Basement Membrane for Inter-Tissue Interactions
The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
research Exploring Pericyte and Cardiac Stem Cell Secretome Unveils New Tactics for Drug Discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
research Elucidating the Anti-Aging Mechanism of Si Jun Zi Tang by Integrating Network Pharmacology and Experimental Validation In Vivo
Si Jun Zi Tang may slow aging by affecting specific cell signaling pathways.
research Advances in Molecular Pathogenesis of Hidradenitis Suppurativa: Dysregulated Keratins and ECM Signaling
Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.
research Direct Reprogramming of Mouse Fibroblasts into Dermal Papilla Cells via Small Molecules
Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.
research Dwarf Planet Ceres and the Ingredients of Life
The Dawn spacecraft found that Ceres has complex organic molecules and a lot of water ice, hinting it might support life.
research HtrA1L364P Leads to Cognitive Dysfunction and Vascular Destruction Through TGF-β/Smad Signaling Pathway in CARASIL Model Mice
The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.
research Hair Follicle Development of Rex Rabbits Is Regulated Seasonally by Wnt10b/β-Catenin, TGFβ-BMP, IGF1, and EGF Signaling Pathways
Winter provides the best fur quality for Rex rabbits due to seasonal changes in specific signaling pathways.
research In Vitro and In Vivo Models for the Development of Hair Growth Materials by Regulating the β-Catenin Signaling Pathways
The research found a way to develop hair growth materials by targeting a specific signaling pathway.
research Alopecia Areata: A Review of Disease Pathogenesis
Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
research Selective Androgen Receptor Modulators Negatively Regulate Triple-Negative Breast Cancer Growth and Epithelial-Mesenchymal Stem Cell Signaling
SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.
research Clionasterol-Rich Fraction of Caulerpa Racemosa Against Particulate Matter-Induced Skin Damage Via Inhibition of Oxidative Stress and Apoptosis-Related Signaling Pathway
A substance from Caulerpa racemosa seaweed may protect against skin damage caused by air pollution by reducing oxidative stress and cell death.
research Wound Healing Protects Against Chemotherapy-Induced Alopecia in Young Rats via Up-Regulating Interleukin-1β-Mediated Signaling
Wound healing can help prevent hair loss from chemotherapy in young rats by increasing interleukin-1β signaling.