31 citations
,
October 2012 in “Dermatologic clinics” This article discusses the use of cosmetic hair care products to improve patient satisfaction in hair loss treatment and reports no new clinical results; the authors emphasize complementing medical interventions with such products.
30 citations
,
August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that TGase 3 may contribute to hair fiber scaffolding by forming specific isopeptide bonds between keratin intermediate filaments and keratin-associated proteins.
29 citations
,
August 2011 in “PubMed” This study describes how shotgun proteomics can identify over 300 proteins in hair shafts, potentially allowing for the diagnosis of diseases through noninvasive human proteome sampling.
28 citations
,
August 2019 in “BMC Genetics” This study identified a target relationship between miR-148a, miR-10a, and BMP7, suggesting these microRNAs influence dermal papilla cell proliferation and may regulate hair follicle growth.
28 citations
,
June 2010 in “Pediatric dermatology” This review discusses short anagen syndrome, highlighting its symptom of abnormally short scalp hair without associated systemic diseases, and notes that hair length often improves spontaneously after puberty without treatment.
27 citations
,
September 2015 in “Current Pharmaceutical Biotechnology” This review discusses the main issues affecting hair health, assesses the safety of certain shampoo ingredients, and highlights areas for future research; it reports no clinical results.
27 citations
,
July 2013 in “Journal of Dermatological Science” The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.
27 citations
,
June 1989 in “Journal of Medical Genetics” This case report describes four patients with hypertrichosis cubiti and short stature, but could not determine a genetic link between hypertrichosis cubiti and skeletal dysplasia.
26 citations
,
May 1984 in “Journal of Parenteral and Enteral Nutrition” In this study, a 54-year-old woman with short bowel syndrome developed biotin deficiency and associated symptoms while on home parenteral nutrition lacking biotin, which improved significantly after supplementation.
25 citations
,
April 2017 in “PloS one” In this study, specific SNPs in the FST gene were significantly associated with various wool quality traits in Chinese Merino sheep, suggesting potential markers for breeding programs.
25 citations
,
August 2015 in “Journal of cosmetic dermatology” This study observed significant differences in hair care practices and biologic hair parameters between Caucasian and African American women, which may contribute to varying hair fragility and growth.
25 citations
,
September 2014 in “SpringerPlus” This study found that sheep possess a polymorphic KAP8-2 gene that shares high sequence identity with the KAP8-2 gene in goats and reindeer.
24 citations
,
January 2018 in “Journal of Pharmacy And Bioallied Sciences” This study found that a licorice-based herbal shampoo offered excellent cleansing ability and user satisfaction without microbial contamination, suggesting potential benefits for hair and scalp issues, but further studies are needed.
24 citations
,
October 2017 in “Scientific reports” This study suggests that controlling light exposure can influence cashmere growth by triggering hair follicles to enter their active growth phase sooner, potentially involving the CSDC2 gene as a key regulator.
24 citations
,
November 2015 in “Annals of Nutrition and Metabolism” This study found that specific SHBG gene variants and haplotypes are associated with polycystic ovary syndrome, suggesting that SHBG may be a candidate gene for the condition.
23 citations
,
August 2022 in “JAMA Dermatology” In this study, patients with alopecia areata indicated a preference for shared decision-making (SDM) with their dermatologists, and those who engaged in SDM reported less decisional regret about their treatment choices.
23 citations
,
May 2020 in “Cell Death and Disease” This study generated FGF5-knockout Dorper sheep using the CRISPR/Cas9 system, resulting in significantly increased fine-wool and active hair-follicle density, and explored downstream signaling pathways for potential applications in androgen alopecia treatment.
23 citations
,
June 2012 in “Molecular Biology Reports” This study found that human outer root sheath cells express VEGF receptor-2, and exogenous VEGF165 significantly stimulates their proliferation through activation of the ERK signaling pathway.
22 citations
,
March 2020 in “Journal of The American Academy of Dermatology” This study found that injecting autologous dermal sheath cup cells significantly increased hair density and diameter in male and female pattern hair loss compared to a placebo for up to 9 months.
21 citations
,
December 1994 in “British Journal of Dermatology” In this study, cultured skin equivalents with ovine hair follicle dermal papillae grafted onto nude mice developed follicle-like structures, suggesting a potential model for studying hair follicle development.
21 citations
,
July 1988 in “Clinics in dermatology” This article reviews haircare practices and hair cosmetics for patients with alopecia, emphasizing healthy scalp maintenance and caution in styling; it reports no new clinical results.
19 citations
,
June 2020 in “Animals” This study found that maternal sub-maintenance nutrition reduced the density and branching ratio of secondary wool follicles in Merino sheep fetuses and identified genes potentially involved in these processes.
19 citations
,
September 2009 in “The Journal of Dermatology” This article discusses the contributions of Dr. Shoji Okuda to the field of hair transplantation and reports no new research findings.
18 citations
,
March 2009 in “Experimental Dermatology” This study suggests that pilomatricoma can differentiate towards various hair follicle structures, including hair matrix, hair cortex, follicular infundibulum, outer root sheath, and hair bulge.
17 citations
,
June 2020 in “Animals” This study identified differentially expressed mRNAs and lncRNAs in Hu sheep hair follicles, suggesting certain genes and pathways are involved in the development of wool curvature patterns.
17 citations
,
February 2013 in “PLOS ONE” This study found that 6-gingerol, a component of ginger, suppresses hair growth rather than promoting it, both in vitro and in vivo, suggesting potential use in hair removal treatments.
16 citations
,
October 2003 in “Journal of The American Academy of Dermatology” This study describes a 4-year-old boy who exhibits a rare, synchronized pattern of hair growth and shedding, unlike the typical asynchronous pattern seen in humans.
16 citations
,
September 2020 in “Animals” This study found that circRNA-1926 promotes hair follicle stem cell differentiation in cashmere goats by sponging miR-148a/b-3p to increase CDK19 expression.
16 citations
,
March 2020 in “Animal Biotechnology” This research explored methods to obtain transgenic sheep embryos expressing synthetic spider silk genes in hair follicles using somatic cell nuclear transfer, with successful in-vitro development observed.
16 citations
,
December 2018 in “Plant Science” This study found that elevated carbon dioxide levels may help mitigate water deficit stress in soybean roots by altering gene expression related to stress and nutrient transport.