Proteomic Analysis of Hair Shaft and Nail Plate

    August 2011 in “ PubMed ”
    Robert H. Rice
    Studysummary This study describes how shotgun proteomics can identify over 300 proteins in hair shafts, potentially allowing for the diagnosis of diseases through noninvasive human proteome sampling.
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    Research cited in this study 9

    1. Mutations in Sterol O-Acyltransferase 1 (SOAT1) Result in Hair Interior Defects in AKR/J Mice Journal of Investigative Dermatology · 2010
    2. Distinguishing Mouse Strains by Proteomic Analysis of Pelage Hair Journal of Investigative Dermatology · 2009
    3. Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding? ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2008
    4. Proteome Analysis of Human Hair Shaft Molecular & Cellular Proteomics · 2006
    5. Cross-Linked Features of Mouse Pelage Hair Resistant to Detergent Extraction ˜The œanatomical record · 1999
    6. Ultrastructural Visualization of Cross-Linked Protein Features in Epidermal Appendages Journal of Cell Science · 1994
    7. Patterns of Expression of Trichocytic and Epithelial Cytokeratins in Mammalian Tissues II: Concomitant and Mutually Exclusive Synthesis of Trichocytic and Epithelial Cytokeratins in Diverse Human and Bovine Tissues (Hair Follicle, Nail Bed and Matrix, Lingual Papilla, Thymic Reticulum) Differentiation · 1988
    8. Formation of the Iε-(γ-Glutamyl)Lysine Crosslink in Hair Proteins: Investigation of Transamidases in Hair Follicles Biochemistry · 1972
    9. Transglutaminase from Hair Follicle of Guinea Pig Proceedings of the National Academy of Sciences · 1972