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A 24-month-old Nigerian girl developed early puberty with no family history, needing treatment her family couldn't afford.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Hair health depends on various factors and hair loss can significantly affect a person's well-being; understanding hair biology is key for creating effective hair care treatments.

The document explains breast development, common breast conditions, and their treatments.

Zinc is crucial for skin health and treating various skin disorders.

Hormones might affect the skin condition hidradenitis suppurativa, but their exact role is unclear.

Androgens can both increase body hair and cause scalp hair loss.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Children's hair grows in different types from before birth through puberty, with growth rates and characteristics varying by age, sex, and race.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.

Lifestyle changes can improve skin health and reduce disease symptoms.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Statins may be linked to reproductive organ conditions, and their risks should be monitored.

The document concludes that careful diagnosis is crucial for chromosome 13q deletion syndrome, tamoxifen can cause reversible eye damage, finasteride may be linked to cataracts, and OCT is useful for diagnosing macular diseases.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.

Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.

Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.

The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.

Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.

Hair is important for protection, social interaction, and temperature control, and is made of a growth cycle-influenced follicle and a complex shaft.

Thermal spring waters and their microbes could be good for skin health and treating some skin conditions in skincare products.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Cirrhosis affects quality of life with various symptoms, requiring a holistic, multidisciplinary approach for management.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.