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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.

Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.

The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Hair proteins in preschool children and their mothers could indicate developmental changes and health status.

Menopause can cause hair thinning and texture changes due to hormonal and metabolic shifts.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

The document discusses male and female pattern hair loss, its diagnosis methods, FDA-approved treatments like finasteride and minoxidil, their side effects, and the role of lifestyle changes.

Sons of mothers with polycystic ovary syndrome (PCOS) have a higher risk of obesity and insulin resistance, possibly due to certain genes and factors passed down from their mothers.

Testosterone is linked to cardiovascular risk factors and stroke, but its exact role is unclear.

Retinoic acid affects male and female muscle energy use and function differently.

Limonin from young citrus fruits may help with hair growth by affecting cell growth and hair cycle pathways.

Hormones and stretching both needed for nipple area skin growth in mice.

Hormones like testosterone and estrogen significantly affect hair growth and structure.

Hair loss peaks in spring and regrowth in late summer, with pregnant females losing the most hair.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Obesity is linked to various skin conditions and issues, and losing weight can improve these conditions.

A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

An 11-year-old girl with compulsive hair pulling was successfully treated with therapy and medication.

Linkus cough syrup is effective and safe with no side effects or toxicity in rats.

Women with PCOS may have a higher risk of severe COVID-19 due to hormonal imbalances and vitamin D deficiency.

Adults should not consume more than 255 micrograms of selenium per day to avoid risk of hair loss and other side effects.

Keratosis pilaris is often linked to genetic mutations and causes skin and hair abnormalities, regardless of those mutations.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.

Autologous Platelet and Extracellular Vesicle-Rich Plasma (PVRP) has potential in enhancing tissue regeneration and improving hair conditions, but its effectiveness varies due to individual differences.