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When treating older patients with both heart valve disease and heart muscle disease, doctors should create personalized treatment plans that address both conditions.

A man with rare skin changes on his fingers was diagnosed with multiple myeloma-linked amyloidosis.

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.

Sodium selenate was found to be safe and possibly slows Alzheimer's progression, but more research is needed.

Human umbilical cord stem cell vesicles may help treat aging and related diseases.

Mesenchymal stem cells could help treat aging-related diseases better than current methods.

A new painless method to collect hair follicles helps study DNA damage and aging.

Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

*Acorus calamus* has many medicinal benefits but needs more safety research.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Compounds from Jatropha cordata bark have significant anti-inflammatory effects and could help with hair loss.

New therapies are being developed that target integrin pathways to treat various diseases.

Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.

Chronic kidney disease can cause hair loss, which may be related to zinc deficiency or certain medications, and sometimes hair grows back when the underlying issue is treated.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

New ginseng compounds may help treat degenerative diseases.

Forsythiasides have multiple health benefits but may cause pseudoallergic reactions, and more research is needed.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.

Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.

New tools show that in fish, NPY increases feeding and somatostatin decreases it.

A woman with undifferentiated connective tissue disease was diagnosed with renal amyloidosis and carpal tunnel syndrome.