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Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Low oxygen conditions increase the hair-growing effects of substances from fat-derived stem cells by boosting growth factor release.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Injected human hair follicle cells can create new, small hair follicles in skin cultures.