research The PDGF/PDGFR Pathway as a Drug Target
The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
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research Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development
Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
research Therapeutic Potential of Stem Cells in Follicle Regeneration
Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.
research Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata
MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
research Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition
Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
research All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration
The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
research Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1
Vitexin Compound 1 may help reduce skin aging caused by UVA light.
research In Vitro Assembly Properties of Human Type I and II Hair Keratins
Different combinations of human hair keratins affect how hair fibers form.
research Identification of Drug-Specific Public TCR Driving Severe Cutaneous Adverse Reactions
Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
research Skin Keratins
Keratins are important for skin cell health and their problems can cause diseases.
research Keratin and Skin Disorders
Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.
research Deficiency of the Human Cysteine Protease Inhibitor Cystatin M/E Causes Hypotrichosis and Dry Skin
Lack of cystatin M/E causes thin hair and dry skin.
research Abstracts
The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.
research In Vitro Assembly and Structure of Trichocyte Keratin Intermediate Filaments
Scientists successfully created mouse hair proteins in the lab, which are stable and similar to natural hair.
research Specific Citrullination Causes Assembly of a Globular S100A3 Homotetramer
A specific chemical change in the S100A3 protein leads to the formation of a four-part structure important for hair formation.
research Anatomy and Function of the Skin
The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
research Comparative Transcriptomic Analysis of Dermal Wound Healing Reveals De Novo Skeletal Muscle Regeneration in Acomys Cahirinus
The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.
research Evolving Approaches to Profiling the Microbiome in Skin Disease
New technologies help us better understand how skin microbes affect skin diseases.
research Microemulsions as Carriers for Therapeutic Molecules
Microemulsions could improve how drugs are delivered and absorbed in the body.
research Discrete Nanoscale Distribution of Hair Lipids Fails to Provide Humidity Resistance
Hair lipids do not protect against humidity.
research Keratin Expression in the Human Hair Follicle
research De Novo Filament Formation by Human Hair Keratins K85 and K35 Follows a Filament Development Pattern Distinct from Cytokeratin Filament Networks
Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.
research Self-Assembly of Dermal Papilla Cells into Inductive Spheroidal Microtissues on Poly(Ethylene-Co-Vinyl Alcohol) Membranes for Hair Follicle Regeneration
EVAL membranes help create cell structures that can regrow hair follicles.
research Formulation of Chloroaluminum Phthalocyanine Incorporated into PS-b-PAA Diblock Copolymer Nanomicelles
The PS-b-PAA copolymer nanomicelles are effective for delivering a cancer treatment drug in photodynamic therapy.
research Molecular Insights Into the Formation of Drug-Polymer Inclusion Complex
The research shows how certain drugs can form stable structures with polymers, which is important for making new pharmaceuticals.
research Molecular Principles of Hair Follicle Induction and Morphogenesis
Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
research Biomaterials and Stem Cells: Promising Tools in Tissue Engineering and Biomedical Applications
Biomaterials combined with stem cells show promise for improving tissue repair and medical treatments.
research Reconstructed Human Skin Shows Epidermal Invagination Towards Integrated Neopapillae Indicating Early Hair Follicle Formation In Vitro
The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
research In Search of Decoding the Syntax of the Bioelements in Human Hair: A Critical Overview
Hair analysis can show nutritional status and environmental exposure, with phosphorus being very stable in hair and differences found based on gender and conditions like depression and autism.
research Production of Mannosylerythritol Lipids and Their Application in Cosmetics
Mannosylerythritol lipids are good for skin and hair care products.