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Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.

Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

The study created a new method to test drugs that affect hormone processing in skin.

Excess androgens may cause PCOS, not just be a symptom.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.

HA-stimulated stem cell vesicles improved hair growth in male mice with androgenetic alopecia.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Some breast cancer patients on hormonal therapy may develop male or female pattern hair loss, which can sometimes be improved with topical treatments.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Hirsutism is too much hair growth in women like the pattern in men, often caused by high male hormones, and can be treated with hormone control and hair removal methods.

Medications for PCOS don't seem to raise heart disease risk.

The effects of estrogen on human scalp hair growth are unclear and need more research.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.