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Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.

The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.

Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.

A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Excess androgens may cause PCOS, not just be a symptom.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

HA-stimulated stem cell vesicles improved hair growth in male mice with androgenetic alopecia.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

The study created a new method to test drugs that affect hormone processing in skin.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Some breast cancer patients on hormonal therapy may develop male or female pattern hair loss, which can sometimes be improved with topical treatments.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.

The effects of estrogen on human scalp hair growth are unclear and need more research.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.

Medications for PCOS don't seem to raise heart disease risk.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

Hirsutism is too much hair growth in women like the pattern in men, often caused by high male hormones, and can be treated with hormone control and hair removal methods.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.