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The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

Early detection and treatment of PCOS in teenagers is important to manage symptoms and prevent severe issues.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Ice-skating athletes often have skin problems due to cold, infections, and inflammation, needing careful treatment and prevention.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

Jojoba oil is highly valued for its diverse medicinal and industrial uses.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

EGF and FGF help hair growth by affecting cell differentiation and fiber growth.

Genetic variations affecting skin structure play a key role in severe acne.

Female pattern hair loss has unclear causes, possibly involving genetics, hormones, and environment, and needs better treatments.

Trichoscopy is good for diagnosing and monitoring hair and scalp problems in children but needs more research for certain conditions.

Hormonal therapies are safe and effective for treating adult women's acne.

Hair treatments like bleaching increase friction by exposing tiny pores on the hair surface.

New hair products are being developed to keep hair and scalp healthy for everyone.

The conclusion is that a new biopsy technique and humidity chamber help study skin mites better and suggest mite overpopulation may cause skin diseases.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

Prolactin may be important for skin growth and immune function.

Oral contraceptives can cause skin issues like dark patches, acne, yeast infections, sensitivity to light, spider veins, skin rashes, and hair loss.

DA liposomes with chloramphenicol effectively target hair follicles and combat MRSA with minimal skin toxicity.