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PCOS is a long-term condition that needs more research for better understanding and treatment.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Skin health and diseases are closely linked to metabolic processes.

Current research explores hair growth drugs, while future research aims for personalized treatments.

Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.

Knowing how skin works and its diseases helps doctors diagnose and treat skin conditions better.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

Hormonal treatments like birth control pills can improve acne in women with excess hair growth and hormone imbalances.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Early treatment and weight management are important for teenagers with PCOS to reduce symptoms and long-term health risks.

Finasteride has different absorption and metabolism in male and female rats, with higher concentrations in certain organs and mostly excreted through feces.

Hidradenitis suppurativa is a chronic skin condition more common in women, linked to genetics and lifestyle factors, and associated with various other health issues.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

PSA might help diagnose PCOS and related skin issues, but more research is needed.

Folliculotropic mycosis fungoides has a worse prognosis than other types, with survival rates varying significantly based on subtype and organ involvement.

Suppressing very long chain fatty acids is linked to skin cancer.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

Golden oyster mushroom extract may protect skin cells from aging by its antioxidant properties.

Mice treatments didn't grow hair, a patient treatment may affect immune response, and people with hair loss often feel anxious or depressed.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Fat-related cells are important for initiating hair growth.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.