17 citations
,
June 2014 in “Journal of Ultrasound in Medicine” This study found that sonography and electron microscopy revealed distinct abnormalities in hair follicle morphology in patients with androgenetic alopecia, which may aid in diagnosing and managing the condition.
17 citations
,
May 2003 in “Journal of The American Academy of Dermatology” This study found that miniaturized hair follicles from pattern alopecia can regenerate rapidly when transplanted onto mice and may grow as well as or better than terminal hairs.
16 citations
,
November 2020 in “International journal of pharmaceutics” This study found that PEGylation of nanoparticles enhances their penetration into hair follicles, with higher molecular weight PEG resulting in deeper follicular delivery.
16 citations
,
December 2018 in “Plant Science” This study found that elevated carbon dioxide levels may help mitigate water deficit stress in soybean roots by altering gene expression related to stress and nutrient transport.
16 citations
,
September 2018 in “Clinical Biochemistry” This paper discusses the link between polycystic ovarian syndrome (PCOS) and health issues like infertility and cardiovascular diseases, caused by both genetic and environmental factors, but reports no new clinical findings.
16 citations
,
February 2018 in “BMC Genomics” This paper reviews genome-based personalized medicine developments using Web services for analyzing SNPs in reproductive potential but reports no new clinical findings.
16 citations
,
July 2016 in “Veterinary Dermatology” This study found that dermoscopy can identify distinctive features in canine pattern alopecia, such as hair shaft thinning and pigmentation patterns, which may aid in diagnosing this and potentially other skin disorders.
16 citations
,
October 2012 in “British Journal of Dermatology” Chemotherapy can cause significant hair thinning and changes in hair texture, while tamoxifen has a smaller effect.
16 citations
,
December 2001 in “Dermatologic Therapy” This review summarizes current genetic knowledge of alopecia areata and provides a theoretical framework for future genetic mapping studies, but reports no new results.
15 citations
,
November 2023 in “Supportive Care in Cancer” In this publication, a collaborative group reviewed the role of dermocosmetics in cancer care and formulated recommendations for using these products to manage skin toxicities and minimize treatment interruptions associated with cancer therapies.
15 citations
,
January 2022 in “Journal of Oleo Science” This study found that a phytosomal delivery system improved the bioavailability of Cuscuta reflexa extract compared to the plain extract, suggesting enhanced potential for this formulation.
15 citations
,
February 2021 in “Scientific Reports” This study identified a specific subpopulation of hair follicle stem cells in mice and humans that are essential for long-term hair regeneration, highlighting the potential for regenerative therapy.
15 citations
,
May 2020 in “Journal of Dermatological Treatment” This systematic review and meta-analysis found that platelet-rich plasma treatments improved hair density and thickness in people with androgenetic alopecia, without serious adverse effects.
15 citations
,
July 2019 in “Journal of Biological Inorganic Chemistry” This study found that finasteride effectively prevented testosterone-induced kidney stone formation in renal tubular cells by reducing COM crystal adhesion and crystallization.
15 citations
,
November 2017 in “Drug Development and Industrial Pharmacy” This study found that the optimized finasteride-loaded lyophilized tablets using a self-nanoemulsifying drug delivery system improved bioavailability in human volunteers compared to the marketed finasteride product.
15 citations
,
February 2017 in “Nursing Clinics of North America” This article reviews common skin reactions associated with epidermal growth factor receptor inhibitors and reports no new clinical findings, emphasizing the need for understanding nursing care and oncodermatology.
15 citations
,
December 2013 This study found that in men with androgenic alopecia, moderate to severe cases were associated with the AA genotype of rs1160312, blood vanadium concentrations, and regular consumption of soy bean drinks.
14 citations
,
June 2021 in “Expert Opinion on Therapeutic Patents” This review discusses various Wnt pathway modulators developed between 2014 and 2020, highlighting their potential as treatments for diseases like cancer and osteoarthritis, but reports no new clinical results.
14 citations
,
April 2021 in “Biology” This study found that ethanol extract of Tubtim Chumphae rice bran downregulates SRD5A gene expression, similarly to finasteride, suggesting potential use as an anti-hair loss product.
14 citations
,
November 2020 in “International Journal of Biological Macromolecules” This study found that Flammulina velutipes polysaccharides-derived scaffolds greatly enhanced wound healing and hair follicle regeneration in a rat model, particularly with the FPS/NaOH variant showing the best results.
14 citations
,
October 2018 in “Brain Research Bulletin” This article reviews the role of exosomes in promoting axonal regeneration and discusses recent findings on how exosome-borne molecules might influence the PTEN-mTOR pathway in injured neurons; it reports no new experimental results.
14 citations
,
September 2014 in “Journal of Pediatric and Adolescent Gynecology” This study found that irregular menstrual cycles in Brazilian adolescents were significantly associated with a higher occurrence of metabolic syndrome and polycystic ovary syndrome indicators.
14 citations
,
October 2000 in “Genomics” This study demonstrated that dermal papilla cells are molecularly distinct from fibroblasts and identified many novel molecules, including a new member of the CTGF protein family.
13 citations
,
May 2022 in “Cell discovery” This study used single-cell RNA sequencing to create a detailed atlas of human scalp hair follicles and found that early-stage hair graying involves matrix hair progenitor depletion linked to P53 pathway activation.
13 citations
,
March 2021 in “British Journal of Pharmacology” This study found that KY19382 can effectively promote hair regeneration and follicle neogenesis in mice and human hair models by activating Wnt/β-catenin signalling, suggesting potential use for alopecia treatment.
13 citations
,
August 2020 in “Mayo Clinic proceedings” In this study, women with lichen planopilaris were found to have high rates of thyroid disease, depression, and anxiety, and about half experienced slowed or stabilized disease progression with treatment.
13 citations
,
November 2019 in “Scientific reports” This study found that inhibiting 5α-reductase in molluscs provokes a specific shell morphology, suggesting gastropods might have unique 5α-reductase substrates absent in vertebrates.
13 citations
,
July 2018 in “General and comparative endocrinology” This study observed that direct exposure to androgens in Western clawed frogs differentially affects thyroid receptor and deiodinase gene expression in male and female tissues, offering insight into sex-specific metabolic pathway activation.
13 citations
,
January 2017 in “Cosmetics” This review discusses in vitro methods for evaluating the effects of hair care products on hair fibers, reporting no new results; the authors emphasize the importance of selecting appropriate and accurate equipment for testing.
13 citations
,
May 2015 in “Journal of The American Academy of Dermatology” This study found that oral minoxidil 5 mg daily significantly improves hair growth in men with androgenetic alopecia, although common side effects include hypertrichosis and pedal edema.