29 citations
,
September 2012 in “Birth Defects Research” This review discusses the developmental regulation of wound healing mechanisms in mammals, focusing on the role of the Wnt and TGF‐β signaling pathways, and reports no new clinical findings.
25 citations
,
October 2020 in “BMC Veterinary Research” This study found that low doses of ivermectin cream enhanced wound healing and reduced scarring by modulating inflammation and growth factor levels, suggesting potential topical use for wound treatment.
23 citations
,
September 2021 in “Clinical Cosmetic and Investigational Dermatology” This review discusses the dermatological applications of botulinum toxin, including off-label uses for various skin conditions, and calls for a better understanding of underlying muscular anatomy for effective clinical practice.
22 citations
,
November 2024 in “Bioactive Materials” This study found that 3D-printed polyamine-modified hydrogels facilitate M2 macrophage polarization and exosome secretion, enhancing skin cell compatibility and promoting wound healing and hair follicle induction in an animal model through specific signaling pathways, suggesting potential for skin disorder therapies.
22 citations
,
December 2017 in “Dermatologic Surgery” This study found that both intralesional PRP and topical tretinoin were effective and safe for treating striae distensae, with PRP being more effective and yielding higher patient satisfaction.
22 citations
,
July 2017 in “Australasian journal of dermatology” This study reported that two Chinese patients with lichen planopilaris or frontal fibrosing alopecia experienced satisfactory hair regrowth for 3-4 years following follicular unit extraction hair transplantation after their conditions were stabilized with therapy.
21 citations
,
July 2018 in “International Journal of Molecular Sciences” This review focuses on the role of the transcription factor Foxn1 in skin biology and discusses its potential implications for regenerative medicine, but reports no new clinical results.
20 citations
,
April 2023 in “Frontiers in Public Health” This study found that psychological and social reporting after trauma with scarring can indicate a person's reaction and susceptibility to psychopathology.
20 citations
,
February 2001 in “Dermatologic Surgery” This study reports that micropigmentation with iron oxide pigments is a safe and effective method for camouflaging scalp scars.
19 citations
,
February 2022 in “Journal of Investigative Dermatology” Mechanical stretching can improve or hinder skin regeneration depending on duration.
16 citations
,
March 2025 in “International Journal of Molecular Sciences” This review analyzed 12 clinical studies on extracellular vesicle therapies, finding potential benefits for skin aging, acne scars, alopecia, and wound healing, but highlighted significant challenges like production standardization and lack of large-scale studies.
14 citations
,
January 2021 in “Scientific Reports” This study found that "micro skin tissue columns" improved wound healing by enhancing re-epithelialization, collagen deposition, dermal remodeling, and reducing inflammation without causing long-term donor site morbidity.
13 citations
,
November 2018 in “Annals of Plastic Surgery” This article presents a surgical approach for nonshaven follicular unit extraction in hair transplantation, describing its application across various conditions with an average graft transection rate of 8.2%.
11 citations
,
January 2007 in “Aesthetic Plastic Surgery” This study found that follicular unit transplantation effectively corrected postrhytidoplasty stigmas like visible scars or displaced hairlines, with high patient satisfaction and a low complication rate.
9 citations
,
January 2023 in “Indian Dermatology Online Journal” This review discusses the use of aesthetic treatments for medical purposes and their therapeutic potential but provides no new clinical results.
9 citations
,
December 1984 in “The Journal of Dermatologic Surgery and Oncology” This article discusses a new method for harvesting donor hair grafts that uses a small area to yield a maximum number of grafts, emphasizing cosmetic improvements with layered suture closure, but reports no clinical results.
8 citations
,
November 2020 in “Optics and Laser Technology” This review discusses the applications and advantages of LED-based photobiomodulation therapy for dermatological and cosmetic purposes but highlights existing challenges and health concerns while exploring future perspectives.
8 citations
,
June 2001 in “International Journal of Cosmetic Surgery and Aesthetic Dermatology” This article reviews methods for managing the donor area in hair restoration surgery to minimize scarring and reports no new results.
8 citations
,
July 1984 in “The Journal of Dermatologic Surgery and Oncology” This study found that using a specific donor row configuration with suturing improves both short-term and long-term scarring, allowing 10-15% more grafts to be taken while maintaining finer donor scars.
7 citations
,
September 2020 in “Frontiers in Cell and Developmental Biology” This study found that recombinant murine IL-36α increased the number of regenerated hair follicles and accelerated wound healing in a mouse model of wound-induced hair follicle neogenesis.
6 citations
,
June 2022 in “Frontiers in Bioengineering and Biotechnology” This study found that a hydrogel containing icariin enhanced wound healing and hair-follicle regeneration in vivo by promoting M2 macrophage polarization and modulating the BMP pathway, with treated skin defects showing improved recovery and new hair follicle development compared to untreated defects.
6 citations
,
September 2017 in “Experimental and Therapeutic Medicine” This study found that two short peptides derived from pigment epithelium-derived factor significantly accelerated full-thickness skin wound healing in mice through mechanisms that may involve increased cell proliferation and stem cell mobilization.
6 citations
,
January 2005 This study evaluated laser excision of the fibrous band for oral submucous fibrosis treatment, noting that while it offers immediate relief, long-term effects require further evaluation due to potential drawbacks.
6 citations
,
May 2004 in “Facial Plastic Surgery Clinics of North America” This review discusses the advancements in surgical hair restoration over the past decade, focusing on optimizing follicular unit transplantation for better aesthetic results, but it reports no new clinical findings.
5 citations
,
September 2019 in “ACS Applied Bio Materials” This study developed a composite hydrogel that delivered multiple proteins, enhancing skin wound healing by accelerating closure and promoting hair follicle regeneration.
5 citations
,
February 2019 in “Oral and Maxillofacial Surgery” Hair loss can be reversed or even cured using advanced hair restoration techniques, with rare complications like swelling and bleeding.
5 citations
,
October 2013 in “Clinics in Plastic Surgery” This article reviews hair restoration surgery techniques, emphasizing procedural insights and highlighting advancements in regenerative medicine and follicular-unit extraction, but it reports no new clinical results.
5 citations
,
January 2004 This paper describes the cellular and molecular processes involved in dermal tissue repair and reports no new experimental results.
4 citations
,
August 2024 in “Dermatological Reviews” This review explores the basic science and therapeutic potential of stem cells, platelet-rich plasma, and exosomes in regenerative medicine, highlighting their promising roles in skin regeneration and repair but noting a need for further research.
4 citations
,
December 2022 in “Frontiers in Bioengineering and Biotechnology” This review discusses the role of exosomes in medical aesthetics, focusing on their mechanisms, production, and preservation, but reports no new clinical results and highlights barriers to their widespread application.