research Sorafenib Stimulates Human Skin Type Mast Cell Degranulation and Maturation
Sorafenib causes skin reactions by increasing the number and activity of skin mast cells.
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research Enhanced Skin Permeation of 5α-Reductase Inhibitors Entrapped into Surface-Modified Liquid Crystalline Nanoparticles
Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.
research Morphological and Morphometric Study of the Androgenetic Alopecic Scalp Using Two- and Three-Dimensional Analysis Comparing Regional Differences
The study found that balding scalps have more thin hairs and larger oil glands, which might contribute to skin conditions related to hair loss.
research Penetration and Distribution of Three Lipophilic Probes in Human Skin Focusing on the Hair Follicle
Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.
research Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, Which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression
Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.
research The In Vitro Use of the Hair Follicle Closure Technique to Study the Follicular and Percutaneous Permeation of Topically Applied Drugs
Hair follicles significantly affect the skin absorption of some drugs.
research ‘You Lose Your Hair, What’s the Big Deal?’ I Was So Embarrassed, I Was So Self-Conscious, I Was So Depressed: A Qualitative Interview Study to Understand the Psychosocial Burden of Alopecia Areata
Alopecia Areata (AA) causes significant emotional distress, including feelings of embarrassment, depression, and anxiety, and impacts social interactions and daily activities.
research The Thinning Top: Why Older People Have Less Hair
Old people have less hair because their hair follicles don't regenerate as well, not because of fewer stem cells, and a protein called follistatin might help reactivate hair growth.
research Frontal Fibrosing Alopecia: Clinical Features, Diagnosis, and Treatment Challenges
Frontal Fibrosing Alopecia is a type of hair loss affecting mostly older women, with no agreed best treatment.
research Trichoscopy Patterns in Alopecia Areata: A Systematic Review and Meta-Analysis
Yellow dots and short vellus hairs are the most common signs of Alopecia Areata (AA), and trichoscopy can help diagnose AA and track treatment progress.
research Alterations in Hair Follicle Morphology and Hair Shaft Production After Follicular Unit Transplantation
Hair transplants can make hair follicles larger and hair shafts thicker.
research Follicular Penetration of Caffeine from Topically Applied Nanoemulsion Formulations Containing Penetration Enhancers: In Vitro Human Skin Studies
Nanoemulsion creams with certain enhancers can greatly increase caffeine delivery through skin.
research Specific In Vivo Ablation of Lrig1-Positive Follicular Stem Cells Results in Sebaceous Gland Loss in Mice
Removing Lrig1-positive stem cells in mice causes temporary loss of sebaceous glands.
research A Study of Plasma Zinc Levels in Thais with Androgenetic Alopecia
People with hair loss have low zinc levels; zinc supplements and laser therapy may help.
research Analysis of the Expression Pattern of the Carrier Protein Transthyretin and Its Receptor Megalin in the Human Scalp Skin and Hair Follicles: Hair Cycle-Associated Changes
The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.
research Regulatory Gamma Delta T Cells Protect Human Scalp Hair Follicles From Alopecia Areata In Vivo
Regulatory γδ T cells help protect hair follicles from alopecia areata and promote hair regrowth.
research Skin Steroidogenesis in Health and Disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
research Methodologies to Evaluate the Hair Follicle-Targeted Drug Delivery Provided by Nanoparticles
Nanoparticle-based drug delivery to hair follicles is more effective when tested under conditions that match skin behavior.
research Finasteride in the Treatment of Men with Androgenetic Alopecia
Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.
research Pattern Hair Loss in Men: Diagnosis, Genetic Link, Clinical Features, and Treatments
Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.
research Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation
Fat under the skin releases HGF which helps hair grow and gain color.
research Permanent Chemotherapy-Induced Alopecia After Hematopoietic Stem Cell Transplantation Treated With Low-Dose Oral Minoxidil
The document concludes that low-dose oral minoxidil successfully regrew hair in a patient with permanent hair loss after chemotherapy and stem cell transplant.
research Effect of Estrogens on Skin Aging and the Potential Role of SERMs
Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.
research Common Causes of Hair Loss: Clinical Manifestations, Trichoscopy, and Therapy
The document concludes that understanding and treating hair loss requires recognizing its various types and using appropriate diagnostic tools and treatments.
research Feily’s Method as a New Mode of Hair Grafting in Prevention of Scalp Necrosis Even in Dense Hair Transplantation
Feily's method prevents scalp necrosis in dense hair transplants by allowing time for blood flow to return before grafting.
research Follicular Unit Transplantation
Follicular Unit Transplantation (FUT) can give great results and patient satisfaction when done carefully and by a skilled surgeon.
research Advances in Scalp Reconstruction
New techniques in scalp reconstruction have improved cosmetic results and reduced complications, especially for large defects.
research Hair Transplantation to Restore Pubic Area
Hair transplant surgery successfully restored a woman's pubic hair, improving her appearance and satisfaction.
research Fabrication and Magnetic Characterization of Cobalt Antidot Arrays: Effect of the Surrounding Continuous Film
Dermoscopy helps dermatologists diagnose different types of hair loss accurately without always needing a biopsy.
research A Clinical Investigation on the Safety and Effectiveness of an Ayurvedic Hair Oil in Controlling Hair Fall in Healthy Adult Human Subjects: A Study on Hair Fall Management
The ayurvedic hair oil is safe and effective for reducing hair fall, promoting hair growth, and improving scalp health.