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Taxane chemotherapy can cause permanent hair loss by damaging hair follicles and altering their DNA.

In this study, researchers developed a microfluidics-based method to generate hair follicle germs on a large scale for potential hair regeneration therapies, demonstrating efficient hair follicle regeneration following transplantation into mice.

Activating cAMP and ATP improves hair growth and strength.

This study describes a distinct variant of lupus panniculitis in East Asians, characterized by reversible, linear alopecia along Blaschko’s lines on the scalp, without systemic lupus erythematosus associations.

This study found that topical application of metformin significantly enhanced skin regeneration in mechanically stretched skin in rats, likely by boosting the proliferation of skin-derived stem cells.

This study found that engineered reconstituted skin can form morphogenetic units that promote tissue patterning and hair regeneration, with certain signaling pathways restoring this ability in adult and fetal cells.

This study reported that treatments using ADSC-CM improved hair growth in all participants, with the most pronounced results after four sessions within three to four months.

This study found that hair follicles across mouse skin form a heterogeneous regenerative field, with distinct cycling dynamics influenced by the balance of activator and inhibitor signals, which could inform other organ regeneration research.

In this study, a new topical formulation containing amine-activated carboxymethyl chitosan and hydrolyzed extracellular matrix showed promising results in a mouse model by reducing oxidative stress, inflammation, and promoting hair regeneration, potentially offering an alternative treatment for inflammatory hair loss.

This study found that when human hair follicles were grafted onto mice, they progressed through dystrophic stages and returned to normal growth, with stem cells aiding in recovery.

In this study, researchers established five new immortalized human dermal papilla cell lines from a male with androgenetic alopecia, which may serve as valuable tools for hair research.

This study found that telocytes in human scalp tissue were located around hair follicles and glands and may be involved in skin regeneration and homeostasis.

This review discusses recent advances in microneedle technology for androgenetic alopecia treatment, focusing on improved follicular delivery and various therapeutic mechanisms, while highlighting challenges in translating preclinical findings to clinical use.

In this study, researchers reported significant hair growth in an 8-year-old with hypotrichosis simplex of the scalp after treatment with a combination of oral botanical extracts and minoxidil, marking the first documented use of botanical extracts as a potential therapeutic approach for this condition.

In this study, bioengineered hair germ microspheres made from HME hydrogels promoted hair follicle regeneration in vivo, suggesting a promising approach for hair loss treatment.

This review synthesizes current research on how the interaction between the skin microbiome and exosome-mediated communication influences hair disorders, and discusses how microbiome restoration and exosome-based therapies could advance treatments for conditions like alopecia by promoting hair regrowth and follicular health.

This study validated a facial aging scale that predicts patients' age with good reliability and validity, potentially serving as a useful tool for assessing facial rejuvenation treatments and clinical research.

This review highlights Shirodhara's potential cosmetic benefits, noting improvements in scalp health, hair growth, and skin appearance, attributed to stress reduction, hormonal balance, enhanced circulation, and nutrient-rich herbal oils.

In this study, extracorporeal shock wave treatment for female pattern hair loss resulted in significant increases in hair count and thickness in 20 women, with 85% of participants perceiving improvements in hair volume.

Disrupted cell interactions in hair follicles contribute to hair loss in androgenetic alopecia.

This article discusses the potential role and mechanisms of platelet-rich fibrin therapies in androgenetic alopecia management, exploring their possible benefits over existing treatments but reports no new clinical results.

This study suggests that platelet-rich plasma's high levels of growth factors may be limited in promoting bone regeneration due to the concurrent release of Dickkopf-1, which inhibits osteogenesis.

In this case study, a 38-year-old woman with female androgenetic alopecia experienced improved hair density, reduced scalp oiliness, and enhanced hair structure after ten microneedle mesotherapy treatments combined with saw palmetto supplementation, with no adverse effects reported.

This review discusses the role of mechanical forces in skin homeostasis and disease development, including their impact on conditions like keloids, androgenetic alopecia, and acral melanoma, and reports no clinical results; the authors propose modifying these forces as a potential therapeutic strategy.

This case report describes an 80-year-old patient whose scalp wound healed by secondary intention, with unexpected hair regrowth observed at 180 days, suggesting hair neogenesis is possible even in older adults.

This review discusses various therapeutic roles of melatonin, particularly its antioxidant and sleep-regulating properties, for skin and scalp conditions, and reports no new clinical results.

This study developed a hair-on-a-chip model that supports the maturation of hair-follicle-like tissue under long-term culture conditions, suggesting its promise for studying hair regeneration and testing scalp-targeted therapies.

This review discusses the potential immuno-regenerative effects of polydioxanone threads in hair loss treatment, focusing on tissue responses and immune modulation, but does not report clinical results.

This preliminary study suggests that hyperbaric oxygen therapy may improve scalp health and follicle activation in healthy adults, with subjective assessments showing significant improvements despite mixed objective findings.

In this preliminary study, HBOT appeared to improve subjective measures of hair and scalp health in healthy adults, but objective changes in follicle density and hair properties were not statistically significant.