6 citations
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February 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that human scalp hair follicles transplanted onto chemotherapy-treated immunodeficient mice closely mimic chemotherapy-induced hair loss seen in cancer patients, providing a valuable model for research.
November 2024 in “International Journal of Cosmetic Science” This study demonstrated that several botanical extracts possess antioxidant properties, reducing oxidative stress and lipid oxidation in scalp treatments, with rosemary extract showing potential to improve scalp condition in a 4-week consumer trial.
July 2023 in “RCMOS - Revista Científica Multidisciplinar O Saber” This narrative review highlights how scalp therapy can enhance service quality in barbershops by integrating trichology, aesthetics, and health education, potentially boosting client loyalty and competitive differentiation in the men's grooming market.
September 2019 in “Journal of Investigative Dermatology” This study established a model using nude mice to successfully graft human scalp skin, maintaining hair follicle growth and skin integrity for at least two months, which may aid preclinical research.
April 2019 in “Journal of Investigative Dermatology” This paper discusses two preclinical models for studying alopecia areata and finds that testing new therapeutic agents should involve both the C3H/HeJ mouse model and the humanized mouse model for comprehensive insights.
3 citations
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January 2008 in “BioTechniques” This systematic review of botulinum toxin for alopecia found inconsistent results on hair growth and highlighted the need for more randomized controlled trials.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study introduces a hypothesis that elevated DHT at puberty may cause chronic thermal stress in specific scalp areas, potentially explaining Androgenetic Alopecia characteristics and guiding future research.
July 2025 in “Journal of Neonatal Surgery” This study utilized U-Net's image-processing capabilities to achieve 92% accuracy in segmenting individual hair strands, enhancing early detection and reliable identification of hair fall areas, which assists in addressing challenges of subtle hair thinning that are difficult to see otherwise.
November 2024 in “Journal of Investigative Dermatology” γδT cells can protect hair follicles from alopecia areata and promote hair regrowth.
63 citations
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September 2009 in “Regenerative Medicine” This study developed a method for expanding human dermal papilla cells in vitro while maintaining their ability to induce hair growth, advancing the potential for follicular cell implantation as a treatment for hair loss.
5 citations
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June 2019 in “British Journal of Dermatology” No results are provided in this article as it lacks an available abstract, making it unclear what effects apremilast and tofacitinib have in a humanized mouse model of alopecia areata.
4 citations
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April 2016 in “Experimental Dermatology” This commentary discusses the mechanisms of progression and potential regrowth in androgenetic alopecia, indicating that the initiation of anagen in kenogen follicles is more critical for hair density improvement than reversing follicle miniaturization.
1 citations
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September 2022 in “Journal of the American Academy of Dermatology” This review examines preclinical studies on exosome therapy for hair loss and reports no new human clinical findings.
April 2024 in “Frontiers in endocrinology (Lausanne)” In this meta-analysis, researchers found that melatonin did not affect primary hair follicles or litter size in goats but was positively correlated with secondary follicle growth, suggesting potential relevance for studying hair growth mechanisms and human alopecia.
January 2011 in “Bradford Scholars (University of Bradford)” This study found that intermediate hair follicles respond to testosterone by growing, but do not respond to finasteride, suggesting they may provide a novel and clinically relevant model for hair growth research.
January 2018 in “Turkiye Klinikleri Journal of Medical Sciences” This study observed that while alopecia treatment in patients showed some improvements in quality of life and anxiety scores at six months, these changes were not statistically significant.
August 2025 in “International Journal of Research Publication and Reviews” This study suggests that stress intensity is highly correlated with hairfall severity, highlighting the potential of an inexpensive and accessible machine learning approach for forecasting and prevention.
August 2024 in “Journal of the National Medical Association” ChatGPT is more accurate at diagnosing hair disorders in lighter skin tones than darker ones.
November 2022 in “Journal of the Endocrine Society” This case study found that a 1.6cm ovarian Leydig cell tumor, causing hyperandrogenism in a postmenopausal woman, evaded detection on standard imaging techniques, underscoring the difficulty of diagnosing such tumors with imaging alone.
9 citations
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September 2018 in “Journal of Photochemistry and Photobiology B-biology” This study demonstrated that combining l-cystine and thiamin in a formulation may protect against UV-induced damage in growth-limited human epidermal keratinocytes in vitro.
22 citations
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January 2014 in “Biological & Pharmaceutical Bulletin” This study found that ginsenoside F2 may suppress hair cell apoptosis and improve hair growth outcomes in a DHT-induced hair loss model more effectively than finasteride.
August 2017 in “International journal of research in dermatology” This study found that topical 0.05% betamethasone dipropionate was the most effective treatment for patients with patchy alopecia areata, with less than 25% hair loss, over a 12-week period, compared to other topical treatments.
October 2025 in “International Journal of Research in Dermatology” This review highlights the benefits of long-pulsed Nd:YAG lasers for hair removal in individuals with Fitzpatrick skin types IV-VI, offering deeper follicular targeting with reduced melanin interaction, and examines emerging technologies like radiofrequency and RF microneedling for safe treatment options in skin of color.
April 2026 in “BMC Biotechnology” This study evaluated a novel synthetic cell-penetrating peptide, DualPep-ALO, finding it promotes hair growth by enhancing follicle cell proliferation, activating regenerative pathways, and reducing inflammation and oxidative stress in vitro and ex vivo, suggesting a promising new topical treatment for hair loss that rivals minoxidil.
11 citations
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August 2013 in “Facial Plastic Surgery Clinics of North America” This review discusses the history and challenges of hair follicle regeneration using follicular fragments and dissociated cells, without presenting new clinical results.
26 citations
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January 2019 in “Experimental Dermatology” This study developed an in vitro system to analyze human skin progenitor cells' ability to form hair peg-like structures, providing insights for engineering hair follicle organoids.
This study developed a three-dimensional model for studying hair follicle development, showing that immortalized dermal papilla cells retain certain differentiation activities and can induce tubule formation in vitro.
February 2025 in “Brazilian Journal of Hair Health” This case study found that multiparametric ultrasound can be an effective non-invasive diagnostic tool for evaluating scalp changes in alopecia areata following repeated corticosteroid injections, potentially offering an alternative to biopsy.
April 2022 in “Journal of The American Academy of Dermatology” This article discusses scalp neuropathy in androgenetic alopecia and suggests that changes in tactile sensation due to Aβ fibers and increased nociception from circ-HTMR may be involved.
5 citations
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April 2024 in “JAAD International” AI can accurately measure hair loss severity in alopecia areata.