141 citations
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February 2005 in “Journal of the American Academy of Dermatology” In this study, oral prednisolone pulse therapy led to significant hair regrowth in some patients with extensive alopecia areata, whereas no improvement was seen in the placebo group.
112 citations
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May 2019 in “Pharmacological Research” This review discusses the isolation, structure, and bioactivity of lignans and neolignans from 2016 to mid-2018, reporting no new clinical results but highlighting their potential protective properties against diseases such as cancer and neurodegeneration.
May 2026 in “Journal of Asia Pacific Aesthetic Sciences” This case report highlights significant hair regrowth in a Malaysian woman with localized alopecia areata after intralesional triamcinolone acetonide treatment at a concentration of 5 mg/mL.
42 citations
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February 1998 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that PNU 157706 is a highly potent inhibitor of human 5α-reductase enzymes, showing a stronger and longer-lasting antiprostatic effect in rats compared to finasteride.
75 citations
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September 1971 in “British Journal of Dermatology” This study found that both intralesional triamcinolone acetonide and triamcinolone hexacetonide promote continuous hair growth in alopecia areata, with effects lasting at least 9 months after a single injection.
18 citations
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January 1988 in “Acta oncologica” This study found that retinol palmitate treatment in patients with stage Ia non-small-cell lung cancer may reduce cancer relapses, but longer follow-up is needed to confirm its efficacy.
January 2015 in “VetPharma” This review discusses Alopecia X in plush-coated dogs, noting that while treatments like melatonin and laser therapy have shown promise, the condition is generally considered a cosmetic issue without the need for therapy.
23 citations
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September 2014 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This case report describes successful CO2 ablation treatment of porokeratotic adnexal ostial nevus in an 8-year-old boy, with marked improvement over a 12-year follow-up.
9 citations
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June 2020 in “Actas Dermo-Sifiliográficas” This source suggests that spironolactone, a potassium-sparing diuretic, is underutilized in dermatology despite evidence showing its potential benefits for female acne, hidradenitis suppurativa, and female androgenetic alopecia, noting its long-term safety and reduced need for additional testing in young women.
January 2014 in “ACTA SCIENTIAE VETERINARIAE” This case report describes a cat with localized scleroderma (morphea-like) that did not show clinical resolution or spontaneous remission after treatment, differing from previously documented cases.
August 2023 in “Journal of Dermatological Science” A specific RNA molecule blocks hair growth by affecting a protein related to hair loss conditions.
39 citations
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January 1977 in “Dermatology” This study found that the retinoic acid derivative Ro 10-9359 cleared psoriasis lesions in over half of the patients, but most experienced side effects, including skin issues and altered liver enzyme levels.
September 2017 in “Zenodo (CERN European Organization for Nuclear Research)” This study suggests that a topical hydroalcoholic extract of liquorice root significantly reduced sebaceous gland size in Syrian hamsters, indicating potential for use in anti-acne therapy.
In this study, introducing the rat OTC gene into spf-ash mice led to increased OTC activity and normalized hair growth and biochemical markers like urinary orotic acid and serum citrulline, partially correcting the symptoms of OTC deficiency.
July 2026 in “Journal of Drug Delivery and Therapeutics” This study evaluated Finasteride-loaded nanostructured lipid carriers for topical use in treating androgenetic alopecia and found that these carriers offer sustained drug release and may reduce systemic side effects compared to oral administration.
October 2023 in “Journal of the American Academy of Dermatology” This source reports that clascoterone cream has been approved in the U.S. for treating acne vulgaris in patients aged 12 and older, suggesting it works by competing with dihydrotestosterone at androgen receptors to mitigate acne's effects.
1 citations
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November 2022 in “Journal of Investigative Dermatology” This study found that ALRN-6924, a clinical-stage dual inhibitor, can selectively protect human scalp hair follicles from paclitaxel-induced toxicity and damage by inducing transient cell cycle arrest in healthy cells without affecting cancer cells, potentially reducing chemotherapy-induced alopecia.
Loose anagen hair syndrome in children may improve with age, but treatment results vary.
April 2017 in “Journal of Investigative Dermatology” This study found that the PON1 192 R allele was associated with an increased risk of psoriasis and altered lipid profiles in patients from Western Mexico.
1 citations
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January 2020 This study found that resveratrol-loaded polymeric nanoparticles show promise as a pulmonary drug delivery system for lung cancer, reducing resveratrol's IC50 significantly in Calu 3 cells.
9 citations
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June 2020 in “Korean Journal of Parasitology” This case report describes the first documented instance of sarcoptic mange in a pet rabbit in Korea, with successful treatment using weekly ivermectin injections leading to full recovery.
34 citations
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July 2011 in “International journal of pharmaceutics” This study found that ion-paired solutions significantly improved the skin penetration of risedronate in hairless mice compared to risedronate alone.
3 citations
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December 2015 in “Acta Veterinaria Brasilica” This study reports a case of ringworm in a Chinchilla lanigera, attributed to stress and contact with canine material contaminated with Microsporum canis.
6 citations
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April 2013 in “Journal of Investigative Dermatology” This study reports that spironolactone use was associated with a decreased risk of developing rosacea compared to other diuretics, particularly in current users without previous androgenic skin disease diagnoses.
2 citations
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February 2025 in “Allergies” In this study, adult hereditary angioedema patients treated with lanadelumab at a Spanish hospital had a 94.1% reduction in angioedema episodes and needed 61% less on-demand medication, showing improved quality of life and minimal adverse effects.
5 citations
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May 2020 in “Clinical and Experimental Dermatology” This correspondence discusses clascoterone as a potential new treatment for androgenetic alopecia but reports no clinical results.
22 citations
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May 2003 in “Planta Medica” This study found that torilin from Torilis japonica fruit extract inhibited 5 alpha-reductase in vitro more effectively than alpha-linolenic acid but less effectively than finasteride.
2 citations
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November 1990 in “International Journal of Dermatology” Albendazole can cause hair loss, and piroxicam can cause fixed drug eruption.
This study found that in a rat model of alopecia, combining low-level laser therapy with Neoptide treatment resulted in better hair regrowth compared to either treatment used alone.
33 citations
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March 1996 in “Veterinary Quarterly” This report describes effective treatment of demodicosis in ferrets using amitraz, marking the first known cases in this species.