Lung Cancer Chemoprevention with Retinol Palmitate: Preliminary Data from a Randomized Trial on Stage Ia Non-Small-Cell Lung Cancer

    January 1988 in “ Acta oncologica ”
    Ugo Pastorino, E. Soresi, M. Clerici, G. Chiesa, P. A. Belloni, Mauro Ongari, Maurizio Valente, Gianni Ravasi
    TLDR Retinol palmitate may reduce cancer relapses in early-stage lung cancer patients.
    The preliminary data from a randomized trial conducted by Pastorino et al. in 1988 investigated the use of retinol palmitate for chemoprevention in patients with stage Ia non-small-cell lung cancer. The study involved multiple departments from various hospitals in Milan, Italy, including the National Cancer Institute and Niguarda Hospital. The findings suggested potential benefits of retinol palmitate in preventing lung cancer progression, although further research was needed to confirm these results.
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