February 2026 in “Journal of Allergy and Clinical Immunology” In this single-cell transcriptomic study, researchers analyzed AA scalp samples and found distinct immune and nonimmune cell activation patterns, with elevated TH1/TH2 and JAK/STAT markers potentially contributing to hair follicle immune privilege disruption and disease severity.
61 citations
,
February 2001 in “American Journal of Obstetrics and Gynecology” This study suggests that polycystic ovary syndrome symptoms are uncommon among women with metabolic syndrome, indicating it may represent only a specific subset within the broader context of metabolic syndrome.
14 citations
,
July 2016 in “Anatomical Science International” This study revealed that in androgenic alopecia, the proximal attachment of the arrector pili muscle to the hair follicle is often lost or significantly reduced.
August 2026 in “Women s Health” This preliminary pilot study found that a combined microneedling-assisted Panax ginseng exosome protocol with adjunctive inner gel use led to short-term improvements in patient-reported vulvovaginal symptoms and qualitative improvements in vulvar skin tone, though results are preliminary and based on a small, uncontrolled sample.
March 2023 in “Journal of the American Academy of Dermatology” This review summarizes evidence that pityrosporum folliculitis in immunocompromised patients responds well to topical antifungals and treatment of underlying conditions, based on a limited number of studies with small sample sizes.
December 2022 in “IntechOpen eBooks” This paper discusses forensic DNA phenotyping, emphasizing its ability to infer visible traits from biological samples without reference samples, but notes ethical and legal concerns related to its use.
23 citations
,
June 2015 in “Clinica Chimica Acta” In this study, researchers identified two potential urinary biomarkers, testosterone–glucuronide and 11α-hydroxyprogesterone, along with four candidate biomarkers, to help understand and diagnose polycystic ovary syndrome.
2 citations
,
May 2022 in “Diagnostics” This study confirmed that 25(OH)D3 can be detected in hair samples from healthy young adults, but no correlation was found between hair and serum 25(OH)D3 concentrations, indicating limited potential as a standalone biomarker.
2 citations
,
May 2021 in “Molecules” This study reports that the metanephrine content was significantly higher in patients with alopecia areata compared to those without the condition.
1 citations
,
May 2025 in “Analytical Science Advances” This study presented a new method for accurately measuring Fe3+ in small serum samples, achieving high recovery rates and agreement with established testing methods, while offering advantages such as cost-effectiveness, simplicity, and enhanced sensitivity.
In this study, the researchers analyzed skin samples from Dun Mongolian horses to uncover molecular pathways linked to the "Bider" marking, identifying differential gene expression and several pigment-related signaling pathways that may play key roles in its formation.
14 citations
,
March 2020 in “Scientific Reports” This study found that dual-frequency ultrasound with microbubble cavitation significantly enhanced minoxidil delivery and hair growth in both lab and animal models compared to single-frequency ultrasound, without damaging the skin in mice.
10 citations
,
June 2018 in “Journal of visualized experiments” This study demonstrated that lactate dehydrogenase activity is notably high in quiescent hair follicle stem cells within mouse skin using a specific enzymatic activity assay.
August 2025 in “Dermatology and Therapy” This study conducted a meta-analysis of gene expression data from alopecia areata patients, identifying 5109 differentially expressed genes and highlighting enriched pathways like JAK-STAT signaling, providing insights into the disease's pathogenesis and potential treatment targets.
This study investigated dual TCR Treg cells in mouse tissues, revealing a high proportion and diverse pairing patterns compared to single TCR Tregs, providing insights into their origins and characteristics across different tissue locations.
August 2024 in “Journal of Home Economics Research” This source reports that among female youths in Umunneochi, common hair care products like serums, sprays, and lotions fall below average usage, and it concludes that consulting dermatologists and avoiding counterfeit products could prevent hair damage.
June 2022 in “Journal of the Liaquat University of Medical and Health Sciences” This study investigated the relationship between lichen planus and dyslipidemia but did not report any clinical findings.
1 citations
,
June 2025 in “International Journal of Plant and Environment” This study found that nickel oxide nanoparticles synthesized using Alternanthera sessilis extract may have potential as antimicrobial, antifungal, and dye-removal agents.
June 2023 in “Benha Journal of Applied Sciences” In this study, researchers isolated gram-positive bacteria from acne lesions in 50 patients, finding that Staphylococcus epidermidis, Staphylococcus aureus, Micrococcus luteus, and Leuconostoc mesenteroides were present at varying frequencies, indicating multimicrobial causes for acne vulgaris.
November 2010 in “Value in Health” Using a call center to collect data in a trial for eye disease in diabetics led to high response rates and very little missing information.
12 citations
,
November 2024 in “Journal of Ovarian Research” This study found that interleukin-1-alpha and oncostatin-M levels were positively associated with PCOS development, while interleukin-7, IL15RA, and CXCL11 were negatively associated, suggesting a connection between inflammatory factors and PCOS.
11 citations
,
January 2010 in “Dermatology Research and Practice” This review discusses the development of human skin with a focus on desmosomes, noting the challenges of translating animal model findings to humans due to species differences and limited human sample access.
93 citations
,
January 2016 in “British Journal of Dermatology” This study found that patients with acne vulgaris had higher serum IGF-1 levels and more intense FoxO1 and mTOR expression than controls, suggesting their role in acne pathogenesis.
61 citations
,
August 1993 in “PubMed” This study found that solid basal cell epitheliomas and the outer root sheath of human hair follicles display nearly identical cytokeratin profiles, suggesting a potential origin connection.
16 citations
,
October 2014 in “Oral surgery, oral medicine, oral pathology and oral radiology” This study found that keratoacanthoma of the lip likely arises from outer root sheath cells, based on the presence of specific keratin markers and periodic acid-Schiff staining patterns.
This study reported that the Fe@C/CB electrocatalyst effectively detected Metol in water samples with a low detection limit, high sensitivity, and good stability, suggesting it as a promising tool for environmental monitoring.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study describes a new method for isolating intact human eccrine glands from scalp follicular units, potentially advancing research on sweat gland physiology.
February 1956 in “Bulletin of Experimental Biology and Medicine” Glycogen levels in mouse skin drop after injury but increase during healing, returning to normal within a month.
36 citations
,
September 2015 in “Forensic Science International: Genetics” This study found that specific DNA variants in the TCHH, WNT10A, and FRAS1 genes are associated with predicting straight hair in Europeans, showing high sensitivity but low specificity, especially using a neural networks approach.
26 citations
,
May 2019 in “PLOS ONE” This study observed that hair follicles in hair loss patients had increased levels of Propionibacterium acnes, potentially linked to elevated immune response gene expression in miniaturized hair follicles.