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This study showed that spironolactone effectively reduces morbidity and mortality in moderate to severe heart failure with reduced ejection fraction, but its benefits in heart failure with preserved ejection fraction are less clear.

In this study, reports from individuals using Serenoa repens indicated a possible post-Serenoa syndrome characterized by persistent sexual and neuropsychiatric symptoms, with causality assessed as 'probable' in 54% of cases, highlighting an underrecognized safety concern that warrants further investigation.

This study reported that derivatization with 5-butylpicolinic acid improved the sensitivity for detecting testosterone and DHT in saliva using LC-ESI-MS/MS, with minimal interference from the saliva matrix.

This study identified seven new compounds from the plant Sansevieria trifasciata Prain and predicted that four of them may have better anti-alopecia activity than minoxidil through an in silico approach.

This study analyzed Sphenodesme involucrata var. paniculata leaves and found high carbohydrate and calcium content, along with several bioactive compounds, supporting their use in traditional medicine for their nutrient-rich properties.

In this study, DMC selectively eliminated senescent cells in old mice, prevented hair loss, improved motor coordination, and reduced senescence-associated secretory factors, suggesting its potential as a senolytic treatment.

This study suggests that setipiprant's inhibitory effect on aldose reductase may contribute to its anti-inflammatory properties, adding a possible mechanism beyond its known action on the prostaglandin D2 receptor.

This study identified compounds from Laportea bulbifera with potential inhibitory effects on human steroid 5α-reductase 2, suggesting their application in treating benign prostatic hyperplasia.

This study discusses the potential of targeting 11β-HSD1 for treating metabolic syndrome and highlights emerging promising data from human trials on selective 11β-HSD1 inhibitors.

This study found that the methanolic extract of Carthamus caeruleus roots significantly reduced inflammation, promoted wound healing, and enhanced hair growth in experimental models, supporting its traditional use in Northern Algeria as a skincare remedy.

This review summarizes recent research and patents on 17β-HSD3, 17β-HSD5, and 3α-HSD3 inhibitors, suggesting their potential in treating androgen-dependent diseases, but reports no new clinical results.

This study isolated and characterized several chemical compounds from the leaves and flowers of Hibiscus rosa-sinensis, using spectral data and chemical reactions for structure elucidation.

This study found that retinoic acid and a retinol complex formulation showed different permeation and compound localization in a skin equivalent model, with unique lipid changes observed with only the retinol formulation.

This study found that sandalwood oil significantly increased alkaline phosphatase activity and expression of hair growth-promoting factors in mice, suggesting its potential role in enhancing hair growth markers.

This review discusses the therapeutic applications of Hibiscus rosa sinensis and reports no new clinical results; the authors highlight its potential in herbal medicine.

This study found that Ishige sinicola extract increased hair growth and cell proliferation in cultured vibrissa follicles and mice, suggesting potential benefits for treating alopecia through β-catenin activation and 5α-reductase inhibition.

This study reported that the aqueous root extract of Hibiscus rosa sinesis significantly reduced inflammation in carrageenan-induced paw edema in swiss albino rats.

This study found that Sol/ASC-DP nanoparticles could enhance the skin permeability of minoxidil due to improved stability and hydrophobic interactions in the nanoparticle structure.

This article reviews the use of Serenoa repens for androgenetic alopecia and highlights a lack of evidence supporting its efficacy, calling for larger clinical trials.

In this study, 4-(4-(phenylaminocarbonyl)benzoyl) benzoic acid exhibited the strongest inhibitory activity against the human type 2 steroid 5α-reductase isozyme among the compounds tested.

This literature review reported limited and low-quality studies on Serenoa repens for androgenetic alopecia, suggesting it may be effective but less so than finasteride, and highlighted the need for better-designed research to confirm its utility.

This case report described a probable case of acute liver injury associated with high-dose S. repens, highlighting the safety concerns of self-medicating with herbal supplements like saw palmetto.

This study found that high concentrations of dimethyl sulfoxide are needed to cause significant swelling in hair fibers, though the swelling is reversible, unlike the effects on skin.

In this study, researchers found that flavonoid glycosides extracted from Dicerocaryum senecioides leaves significantly promoted hair growth in BalB/c mice, with the shortest hair growth completion time of 19 days compared to the control's 29 days, and dose-dependent results.

This research reports that transglucosylation significantly improved the water solubility of baicalin through the synthesis of baicalin glucosides, with BG1 and BG2 showing enhanced solubility and potential biological activity similar to baicalin in antioxidant and anti-glycation assays.

This study reported that administering salicylates to wounds in adult mice promoted wound healing patterns similar to embryonic wounds, enabling complete wound regeneration and reduced scarring by activating AMPK and subsequent signaling pathways.

In this study, a newly designed protein degrader targeting androgen receptors showed promise in reversing hair regrowth inhibition in a mouse model of androgenetic alopecia, suggesting potential as a novel and safe treatment strategy.

The researchers reported that carnosic acid and carnosol, extracts from rosemary leaves, specifically inhibit S. aureus virulence expression, suggesting potential topical treatments for atopic dermatitis flares.

This study found that 60% of examined prostate tumors had new somatic substitutions in the SRD5A2 gene, affecting enzyme activity and potentially influencing prostate cancer progression.