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Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

A specific drug can help treat Lichen Planopilaris, a condition causing permanent hair loss.

All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

Goat skin changes with the seasons due to genes affected by daylight and hormones.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.

Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.

Keratin 79 is linked to liver damage and may help diagnose liver diseases.

Topical retinoids effectively improve photodamaged skin.

Activating Nrf2 can help protect against hearing loss.

Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.

Vitamin A helps skin stem cells decide their function, aiding in hair growth and wound repair.

Light affects skin health, aging, and cancer risk, and new light-based treatments and imaging are promising for skin care.

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Isotretinoin can cause serious birth defects and needs careful use, especially in pregnant women.