January 2006 in “Journal of Rural Medicine” This review discusses recent Japanese research on trichotillomania and compares it with international studies, reporting no new clinical results.
June 1982 in “Revista Colombiana de Obstetricia y Ginecología” This article discusses treatments for androgenic manifestations using cyproterone acetate alone or with estrogens, but it does not provide new clinical results.
October 2019 in “International journal of clinical & experimental dermatology” This study found that female pattern hair loss significantly reduces quality of life, particularly among younger patients, those with longer disease duration, and individuals with diagnosed mental health issues.
This thesis reviews the psychological and social challenges faced by men and women with androgenetic alopecia who seek treatment, but reports no new results.
4 citations
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May 2025 in “International Journal of Nanotechnology and Nanomedicine” This review highlights recent advances in the design of nanocarrier systems for transdermal drug delivery, detailing their potential to improve treatment precision for dermatologic conditions despite challenges like formulation stability and scalability.
14 citations
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March 2022 in “Macromolecular Rapid Communications” This review discusses the current state and potential future of polymer-based microneedles for transdermal drug delivery, without reporting new empirical results; it highlights their applications and existing challenges.
21 citations
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December 2016 in “European journal of pharmaceutics and biopharmaceutics” This study found that nano-sized lipid particles improved the skin accumulation and retention of dexamethasone compared to a base cream, suggesting potential benefits for inflammatory skin disease treatment.
128 citations
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July 2009 in “International Journal of Pharmaceutics” This study found that penetration enhancer-containing vesicles significantly improved minoxidil delivery to the skin compared to traditional liposomes and penetration enhancer-containing ethanolic solutions, with deformability linked to enhanced deposition.
2 citations
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August 2020 in “Chemical and Pharmaceutical Bulletin” This study found that rubbing increased caffeine permeation into skin primarily via hair follicles, especially when applied against the natural hair direction.
February 2024 in “Current Drug Delivery” In this study, researchers developed an emulgel formulation containing minoxidil for hair growth, using chitosan and fucoidan as gelling agents, achieving controlled drug release with 99.7% released by the 12th hour.
48 citations
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April 2019 in “ACS Applied Materials & Interfaces” In this study, researchers introduced calcium carbonate-based carriers for transdermal drug delivery, observing efficient transport of substances and systemic absorption in rats, suggesting potential applications in regenerative medicine and dermatology beyond conventional topical treatments.
14 citations
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July 2007 in “Therapy” This review discusses ethosomes as potential carriers for delivering drugs into deeper skin layers and provides no new clinical results, suggesting a need for further studies on their efficiency in dermal therapies.
March 2024 in “ACS Applied Materials & Interfaces” This study developed a delivery platform using hyaluronic acid-based dissolvable microneedles with nanoliposomes containing kopexil and kopyrrol, which showed improved hair regeneration for treating androgenetic alopecia in vivo at lower dosages compared to minoxidil.
1 citations
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December 2023 in “Annals of Phytomedicine An International Journal” In this review, the researchers discuss how nanoemulgel overcomes the limitations of lipophilic phytomolecules by improving their bioavailability, penetration, and therapeutic efficacy, making it a promising nanocarrier for the treatment of various health conditions.
20 citations
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August 2014 in “Therapeutic delivery” This article reviews potential applications and challenges of using the transfollicular route for drug delivery but does not present new clinical findings; it calls for further exploration and development in this field.
55 citations
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January 2002 in “Journal of liposome research” This research explores developing liposomal formulations to enhance the delivery of difficult-to-absorb agents directly to hair follicles and sebaceous glands, with minoxidil and plasmid DNA as study molecules.
September 2024 in “Medical Sains Jurnal Ilmiah Kefarmasian” This review summarizes the potential of nanostructured lipid carriers in drug delivery systems, highlighting their promise in enhancing the stability and skin penetration of anti-aging cosmetics.
59 citations
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January 2015 in “Nanoscale” In this study, polymeric micelles containing retinoic acid were found to improve targeted delivery to hair follicle structures in human skin more efficiently than a marketed retinoic acid gel, suggesting potentially safer and more effective acne treatment.
202 citations
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June 2005 in “Aaps Pharmscitech” This review discusses the potential of lecithin organogels for improving topical drug delivery and presents no new experimental results; the authors highlight their stability and low skin irritancy as advantages.
9 citations
,
June 1998 in “Dermatologic Surgery” In this pilot study, the Rapid Fire Hair Implanter Carousel facilitated graft placement in hair transplantation by reducing bleeding and operative time compared to the traditional manual method.
1 citations
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December 2025 in “Iraqi Journal of Pharmaceutical Sciences ( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512)” This study investigated spanlastic nanovascular drug delivery systems and found that they can effectively enhance the transport and continuous release of medicines with small particle size, low polydispersity index, and satisfactory entrapment efficiency, showing potential as carriers for drug delivery.
January 2014 in “Journal of Physiology & Pathology in Korean Medicine” Microneedle roller therapy can help hair grow.
2 citations
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October 2022 in “Journal of Sustainable Materials Processing and Management” This research found that Nano-Transfersomes containing Vitamin E and aloe vera showed improved permeability and prolonged drug release compared to a marketed formulation, with no skin irritancy observed in mice, potentially offering a sustainable and biocompatible option for psoriasis management.
10 citations
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May 2016 in “Polymer” This study reports that novel core-ABS nanocarriers efficiently loaded with dexamethasone and finasteride show potential for dermal drug delivery, exhibiting non-toxic interactions with human keratinocyte cells and skin penetration.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This paper discusses ethosomal drug delivery systems, highlighting their improved ability to enhance skin penetration and increase therapeutic effectiveness in treatments like acyclovir for herpes labialis and minoxidil for androgenic alopecia compared to standard formulations.
July 2025 in “International Journal of Science and Research (IJSR)” This research outlines the potential of nanoemulgels as a superior alternative to conventional topical treatments, noting their ability to improve skin permeability, drug release, and therapeutic targeting, though challenges remain in formulation stability and consistency.
This study developed a topical dutasteride-loaded Insitu-emulgel for treating androgenetic alopecia, finding it effectively controls drug release, enhances skin penetration, and may improve patient compliance compared to traditional topical treatments, though further clinical research is underway.
December 2023 in “Azerbaijan Pharmaceutical and Pharmacotherapy J” This study formulated a minoxidil-loaded submicron emulsion-based topical gel, which demonstrated effective in vitro release, ex vivo permeation, and stability, suggesting it may offer a targeted treatment approach for alopecia compared to traditional methods.
2 citations
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September 2016 in “Journal of Dermatological Science” This study reported that squarticles, nanoparticle carriers made from sebum-derived lipids, significantly enhanced minoxidil delivery to hair follicles in vitro, increasing follicular uptake sevenfold and minimizing systemic absorption compared to a free control solution, while showing good skin tolerability.
3 citations
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December 2024 in “Iraqi Journal of Pharmaceutical Sciences ( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512)” This study reported that meloxicam-loaded spanlastics, created using the ethanol injection method, demonstrated potential as a drug delivery system with sustained release and effective entrapment efficiency.