Formulation and Evaluation of Minoxidil Loaded Submicron Emulsion Based Topical Gel for Treatment of Alopecia

    December 2023 in “ Azerbaijan Pharmaceutical and Pharmacotherapy J ”
    Jasjeet Kaur Narang, Ramandeep Singh Narang, . Mehak
    Image of study
    TLDR The minoxidil gel could be a better treatment for hair loss than traditional forms.
    The study formulated a minoxidil-loaded submicron emulsion-based topical gel for alopecia treatment. The emulsion was prepared using Clove oil, Tween 20, and Transcutol P, with the optimized formulation (M5) showing a pH of 5.4, in vitro release of 95.08%, ex vivo permeation of 79.36%, and a particle size of 181.3nm. The M5 formulation was then converted into a gel using Carbopol 934. The gel showed anti-oxidant potential and remained stable for three months. The study concluded that this minoxidil-loaded submicron emulsion-based topical gel could be a beneficial nano-approach for treating alopecia compared to traditional topical dosage forms.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Hair has only gotten worse ~10 months on minoxidil.

      in Minoxidil  1 upvotes 2 days ago
      The user experienced worsening hair loss despite using finasteride and topical minoxidil, and is considering switching to dutasteride and oral minoxidil. They also tried microneedling and tretinoin with minoxidil, and are exploring Sulfogenz topical minoxidil.

      community Let's talk about the use of minoxidil 15%

      in Minoxidil  3 upvotes 3 days ago
      Minoxidil 5% is no longer effective for the user, who is considering stronger minoxidil or oral options despite availability issues. Suggestions include trying minoxidil 15%, oral minoxidil, microneedling, and exploring other treatments like finasteride and dutasteride.

      community Insane shedding after upping minoxidil dose.

      in Minoxidil  1 upvotes 1 week ago
      The user experienced increased hair loss after increasing their minoxidil dose to 5mg and is considering switching to dutasteride while on testosterone replacement therapy. They are also using finasteride, microneedling, and considering adding Nizoral and caffeine serum to their regimen.

      community When do you see results with foam minoxidil ? 110 days of use so far

      in Minoxidil  2 upvotes 1 week ago
      The user has been using foam minoxidil for 110 days and recently added topical finasteride to address hair loss, particularly at the crown, and is experiencing some baby hair growth at the hairline. They are considering adding tretinoin and are advised to be patient, as results can take up to 6 months, with consistency being key.

      community Duoxidil, Dutasteride and oral Minoxidil

      in Minoxidil  85 upvotes 1 week ago
      The conversation discusses hair regrowth treatments, specifically using a combination of oral and topical minoxidil, oral and topical dutasteride, and PRP. There is skepticism about the authenticity of the results, with some users questioning the changes in hair and skin appearance.

    Similar Research

    5 / 1000+ results