3 citations
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January 2023 in “International Journal of Cosmetic Science” This review discusses recent patents on the cosmetic use of coffee and its by-products, highlighting their potential as promising topical formulation ingredients with skin health benefits.
October 2025 in “Food science and nutrition” This chapter explores the evolving cultural and scientific significance of coffee, highlighting how traditional beliefs, brewing innovations, and globalization have shaped its consumption and cultural impact across different societies.
July 2023 in “International journal of research publications” In this study, topical application of 45% robusta green coffee bean extract in male wistar rats did not significantly enhance hair growth but effectively inhibited the increase of 5α-reductase type 1 levels when exposed to testosterone.
December 2025 in “Revista em Agronegócio e Meio Ambiente” This study investigated the effects of ultrasound-assisted extraction on sunflower seed oil mixed with defective green coffee grains, finding that higher coffee grain ratios decreased oil yield but increased phenolic content and antioxidant activity, with potential applications for wound treatment.
1 citations
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March 2022 in “Protection convergence” This study found that double-fermented green coffee bean extracts displayed strong antioxidant, anti-inflammatory, and dermal papilla cell growth-promoting activities, suggesting potential use in cosmetics for scalp and hair health.
January 2022 in “UiTM Institutional Repositories (Universiti Teknologi MARA)” This study suggests that coffee ground extract may accelerate hair growth in rabbits, potentially due to its caffeine content.
December 2023 in “Asian journal of beauty & cosmetology”
In this study, the SFE-4 extract from coffee pulp demonstrated potential effects for treating androgenetic alopecia by enhancing cell proliferation and gene expression related to hair growth pathways in vitro, using human hair follicle dermal papilla and prostate cancer cells.
October 2018 in “IOP conference series. Materials science and engineering” In this study, treatment 3 using coffee extract resulted in faster hair growth and greater hair weight in test animals over 21 days compared to other treatments.
1 citations
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January 2020 in “Journal of Biosciences and Medicines” This study found that a 5% gel with hydroalcoholic extract from black pop bean integument may have a photoprotective effect in mice exposed to UV-C radiation.
May 2026 in “Revista Iluminart” In this study, researchers found that adding coffee grounds to neutral shampoo, a popular DIY trend, resulted in peak caffeine extraction after seven days, with concentrations surpassing those in commercial products, suggesting educational potential for chemistry classes.
January 2026 in “AAPS PharmSciTech” In this study, a novel liposomal formulation combining caffeine and cafestol significantly enhanced their penetration into human skin layers, with formulation F9 doubling caffeine and greatly increasing cafestol levels in the dermis, suggesting potential for improved topical delivery.
January 2010 in “Research and Practice on Chinese Medicines” This study found that coffee extraction and its active compound, caffeotannic acid, showed high enzyme inhibition activity against 5a-reductase in an in vitro model.
This study found that low-temperature rendering of black beans, peony, and green tea extracts retains higher antioxidant properties and effectively supports scalp health by strengthening follicles and moisturizing the scalp.
This study found that a cream containing 20% broad bean extract may reduce axillary hair growth, but only some outcomes were statistically significant compared to placebo.
January 2026 in “Reproductive Toxicology” In this study, daughters of mothers who consumed 8 or more cups of coffee per day during pregnancy experienced pubertal development about 2 months earlier than daughters of mothers who did not consume coffee, whereas no such differences were observed among sons.
October 2017 in “Universidad Nacional de Trujillo” This study found that low doses of hydroethanolic extract from Coffea arabica L. seeds reduced prostatic growth in mice with induced prostatic hyperplasia, while both low and high doses lowered uric acid and PSA levels.
August 2024 in “Cosmetics” This review highlights caffeine's diverse benefits in cosmetics and nutricosmetics, noting its antioxidant properties, ability to treat skin disorders like androgenic alopecia, and potential to enhance sunscreen effectiveness, though penetration into deeper skin layers remains challenging.
This review discusses caffeine's biological activities relevant to cosmetics, such as antioxidant effects and potential benefits for hair growth, but reports no clinical results; the safety considerations are addressed.
1 citations
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February 2018 in “Psicologia e Saúde em Debate” This study explored the preformulation of a caffeine-containing shampoo for treating androgenic alopecia and found the formulation to be stable and viable for compounding.
12 citations
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December 2023 in “Journal of Applied Pharmaceutical Sciences and Research” In this research, caffeine's versatile pharmacological actions were highlighted, demonstrating its stimulant, bronchodilator, diuretic, and potential anticancer effects through interactions with adenosine receptors, phosphodiesterase, and renal tubules, revealing valuable insights for drug development and therapeutic applications in medicine.
4 citations
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September 1999 in “Journal of Clinical Forensic Medicine” Caffeine in hair might help identify people, but it's not always reliable.
55 citations
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March 2005 in “Neuropharmacology” A neurosteroid can reduce caffeine-induced anxiety in rats.
December 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses the potential benefits of using topical caffeine products for treating androgenic alopecia but reports no new clinical findings; the authors highlight caffeine's possible positive effects based on existing studies.
February 2025 in “International Journal of Advanced Research in Science Communication and Technology” This review highlights the potential benefits of fenugreek seed-based oils for hair health, suggesting they may enhance scalp health and hair growth while reducing conditions like dandruff and hair loss.
5 citations
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January 2020 in “Journal of Dermatology and Dermatologic Surgery” This review discusses the potential dermatological benefits of caffeine for hair growth, rosacea, and skin cancer, but notes significant limitations in available research.
August 2015 in “Arquivo Brasileiro de Medicina Veterinária e Zootecnia/Arquivo brasileiro de medicina veterinária e zootecnia” This study found that maternal caffeine intake during gestation and lactation can lead to skin lesions like hypotrichosis and alopecia in both mother and offspring rats, irrespective of maternal cortisol levels.
75 citations
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May 2013 in “Journal of the American Academy of Dermatology” This review examines skin symptoms, diagnosis, and treatment of zinc deficiency in children, proposing a classification system but reporting no new clinical results.
67 citations
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February 2020 in “Journal of Ginseng Research” This review evaluates and classifies the non-saponin components of Korean Red Ginseng, emphasizing their combined role with saponins in the plant's bioactivity, but reports no new clinical results.