Skin Penetration of Caffeine and Cafestol Using Liposomes: Exploring the Benefits of a Combined Delivery System
January 2026
in “
AAPS PharmSciTech
”
Studysummary In this study, a novel liposomal formulation combining caffeine and cafestol significantly enhanced their penetration into human skin layers, with formulation F9 doubling caffeine and greatly increasing cafestol levels in the dermis, suggesting potential for improved topical delivery.
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